Results 151 to 160 of about 2,966,724 (259)

Development of auditory and spontaneous movement responses to music over the first postnatal year. [PDF]

Elife
Nguyen T, Bigand F, Reisner S, Koul A, Bianco R, Markova G, Hoehl S, Novembre G.   +7 more
europepmc   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Socio-affective development in infants with Down' s Syndrome. 'Desarrollo socio-afectivo en niños con síndrome de Down'

, 1990
El libro es el resultado de la compilación de las colaboraciones de expertos internacionales reunidos en un Simposio Internacional sobre Psicología y Psicobiología Educativa e Integración Social de las personas con Síndrome de Down, organizado por Juan ...
Pérez López, Julio, Candel Gil, Isidoro, Carranza Carnicero, José Antonio   +2 more
core  

Controlled Retrieval Relies on Directed Interactions between Semantic Control Regions and Visual Cortex: MEG Evidence from Oscillatory Dynamics. [PDF]

J Neurosci
Eisenhauer S, Zhang M, Krieger-Redwood K, Aveyard R, Jackson RL, Cornelissen PL, Smallwood J, Jefferies E.   +7 more
europepmc   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Altered cognitive performance is associated with auditory cortex functional connectivity in patients with unilateral sensorineural hearing loss. [PDF]

Front Neurosci
Chen J, Wang B, Yu Y, Zhou X, Zhao Y, Wen X, Qin R, Guan Y.   +7 more
europepmc   +1 more source

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

The Relation of Different Concepts of Causality in Econometrics [PDF]

Granger and Sims non-causality (GSNC) are compared to non-causality based on concepts popular in the microeconometrics and programme evaluation literature (potential outcome non-causality, PONC).
Michael Lechner
core  

Behavioral engagement and stimulus regularities coordinate auditory-prefrontal network activity. [PDF]

PLoS Biol
Xu H, Song P, Ye H, Lao-Rodríguez AB, Zhang Q, Zhai Y, Bao X, Mehmood I, Tanigawa H, Tu Z, Zhang L, Zhao X, Pérez-González D, Malmierca MS, Yu X.   +14 more
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source