Results 191 to 200 of about 208,822 (261)

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

The 100 top-cited articles in menopausal syndrome: a bibliometric analysis. [PDF]

Reprod Health
Jin Z, Tian C, Kang M, Hu S, Zhao L, Zhang W.   +5 more
europepmc   +1 more source

The 100 Top-Cited Articles about Kienböck's Disease: A Bibliometric Analysis. [PDF]

J Hand Microsurg, 2022
Afshar A, Tabrizi A.
europepmc   +1 more source

Multifunctional E‐Tattoos Based on Electrospun PVBVA Fibers Coated with Ti3C2Tx MXene for Energy Harvesting, Energy Storage, and Biometric Sensing

Advanced Science, EarlyView.
This study explores a novel E‐tattoo made from PVBVA fibers coated with Ti3C2Tx MXene. The device is designed to harvest energy directly from the human body, providing power for itself. The research demonstrates the E‐tattoo's capability for charge storage and its potential for health monitoring through integrated ECG and EMG sensing, all within a ...
Ajay Pratap, Fereshteh Rajabi Kouchi, Tony Valayil‐Varghese, Hailey Burgoyne, Attila Rektor, Michael Curtis, Miranda Lea Nelson, Francis N. Mokogwu, Corey M. Efaw, Josh Eixenberger, Allyssa Bateman, Benjamin C. Johnson, Brian Jaques, Zhangxian Deng, Kurtis Cantley, Christopher E. Shuck, David Estrada   +16 more
wiley   +1 more source

A Bibliometric Analysis of the Top Cited Articles in Sports and Exercise Medicine. [PDF]

Orthop J Sports Med, 2021
Khatra O, Shadgan A, Taunton J, Pakravan A, Shadgan B.   +4 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

The 100 top-cited articles on chronic kidney disease-mineral and bone disorder: A bibliometric analysis. [PDF]

Medicine (Baltimore)
Kang T, Mao H, Zhang D, Tang D, Ou S.
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Integrated Ultrasound Device for Precision Bladder Volume Monitoring via Acoustic Focusing and Machine Learning

Advanced Science, EarlyView.
We present a conformable wearable ultrasound patch for noninvasive bladder volume monitoring. A flexible PZT array combined with a concave acoustic lens concentrates acoustic energy and improves depth selectivity through the anterior pelvic wall.
Long Long Cao, Feng Wen Wang, Jingwei Xue, Fulei Liu, Ming Liang Jin   +4 more
wiley   +1 more source

The 100 Top-Cited Articles on Medial Patellofemoral Ligament: A Bibliometric Analysis and Review. [PDF]

Orthop J Sports Med
Panagopoulos A, Giannatos V, Antzoulas P, Lakoumentas J, Raoulis V, Hantes M.   +5 more
europepmc   +1 more source