Results 41 to 50 of about 214,642 (241)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Top 100 Most-Cited Articles on Enhanced Recovery After Surgery: A Bibliometric Analysis and Visualized Study

open access: yesFrontiers in Surgery, 2022
BackgroundThe enhanced recovery after surgery (ERAS) protocol is widely implemented in surgeries, and this study aims to reveal the characteristics of the 100 most-cited original articles in the field of ERAS research.MethodsThe literature was retrieved ...
Liping He   +4 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Top 50 most-cited articles on craniovertebral junction surgery

open access: yesJournal of Craniovertebral Junction and Spine, 2017
Background: Craniovertebral junction is a complex anatomical location posing unique challenges to the surgical management of its pathologies. We aimed to identify the fifty most-cited articles that are dedicated to this field.
Nima Alan   +6 more
doaj   +1 more source

The top 100 most-cited papers in pheochromocytomas and paragangliomas: A bibliometric study

open access: yesFrontiers in Oncology, 2022
BackgroundThe purpose of this study was to define and analyze the characteristics of the top 100 most-cited articles and reviews on the topic of pheochromocytomas and paragangliomas (PPGLs) by using bibliometric methods.MethodsWe explored the Web of ...
Sai-Li Duan   +11 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The 100 Top-cited Articles in Main Allergy Journals: A Bibliometric Analysis

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2019
The objective of this study was to identify the characteristics of the top 100 cited studies in main allergy journals. The 100 top-cited studies in allergy journals from the Web of Science were enrolled.
Yonggang Zhang, Liuliu Quan, Liang Du
doaj   +1 more source

Top 100 Cited Articles on Lumbar Spondylolisthesis: A Bibliographic Analysis

open access: yesGlobal Spine Journal, 2020
Study Design: Bibliographic analysis. Objective: The aim of this study is to identify the most cited studies on lumbar spondylolisthesis and report their impact in spine field.
Khalifah Aldawsari MBBS   +2 more
doaj   +1 more source

Characteristics of Publications on Occupational Stress: Contributions and Trends

open access: yesFrontiers in Public Health, 2021
This study aimed to analyze the bibliometric characteristics of the publications on occupational stress and highlight key research topics and future trends.
Yang Zhang   +7 more
doaj   +1 more source

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