Results 91 to 100 of about 1,548,118 (340)
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
STUDENTS’ READING STRATEGIES AT ENGLISH EDUCATIONAL DEPARTMENT
Al-Ishlah: Jurnal Pendidikan, 2019 Reading comprehension is one of the skills that students must have to enrich their knowledge, especially university students. There are two kinds of reading strategies: Top – Down strategy and Bottom – Up Strategy.
Utami Dewi, Maryati Salmiah
doaj +1 more source
Robust top-down and bottom-up visual saliency for mobile robots using bio-inspired design principles [PDF]
, 2021 Uziel Jaramillo-Avila +3 more
openalex +1 more source
An empirical resource for discovering cognitive principles of discourse organisation: the ANNODIS corpus [PDF]
, 2012 International audienceThis paper describes the ANNODIS resource, a discourse-level annotated corpus for French. The corpus combines two perspectives on discourse: a bottom-up approach and a top-down approach.
Afantenos, Stergos +13 more
core +3 more sources
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Computer-aided design of nano-filter construction using DNA self-assembly
Nanoscale Research Letters, 2006 Computer-aided design plays a fundamental role in both top-down and bottom-up nano-system fabrication. This paper presents a bottom-up nano-filter patterning process based on DNA self-assembly.
Mohammadzadegan Reza, Mohabatkar Hassan
doaj +1 more source
In_Bo, 2015 Today architecture has to design for rapidly changing futures, in a citizen-centered way. That is, architecture needs to embrace meaningful design. Societal challenges ask for a new paradigm in city-making, which combines top-down public management with ...
Ingrid Mulder
doaj +1 more source
Learning to design for social sustainability through the synthesis of two approaches [PDF]
, 2013 This paper brings together research that I was involved in the SUE –MOT (sustainable urban environments; metrics models and toolkits) funded by the EPSRC (completed in 2010) and my work in Sri Lanka on a pioneering project to relocate Canal Bank dwellers
Paranagamage, Primali
core
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Small amphipathic peptides are responsible for the assembly of cruciferin nanoparticles
Scientific Reports, 2017 Amphipathic peptides are versatile building blocks for fabricating well-ordered nanostructures, which have gained much attention owing to their enormous design possibilities and bio-functionalities.
Hui Hong, Ali Akbari, Jianping Wu
doaj +1 more source