Results 101 to 110 of about 1,475,669 (329)
Top down, bottom up structured programming and program structuring [PDF]
New design and programming techniques for shuttle software. Based on previous Apollo experience, recommendations are made to apply top-down structured programming techniques to shuttle software.
Hamilton, M., Zeldin, S.
core +1 more source
Using the Personal Competence Manager as a complementary approach to IMS Learning Design authoring [PDF]
, 2008 Vogten, H., Koper, R., Martens, H., & Van Bruggen, J. (2008). Using the Personal Competence Manager as a complementary approach to IMS Learning Design authoring.
Koper, Rob +3 more
core +2 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Curriculum Designs: Top-down or Bottom-up? —A Case Study in a Technological School of China
Theory and Practice in Language Studies, 2019 Competitive education around the world brings up many issues about curriculum design. In order to cultivate the ideal talents with abundant knowledge of language and specialties, it is necessary to design appropriate curricula. This comparative study has been carried out to discuss the appropriateness of curriculum designed for two parallel groups of ...
openaire +2 more sources
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
An empirical resource for discovering cognitive principles of discourse organisation: the ANNODIS corpus [PDF]
, 2012 International audienceThis paper describes the ANNODIS resource, a discourse-level annotated corpus for French. The corpus combines two perspectives on discourse: a bottom-up approach and a top-down approach.
Afantenos, Stergos +13 more
core +3 more sources
Molecular Oncology, EarlyView.Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan +4 more
wiley +1 more source
The FEM-2 parallel computer is designed using methods differing from those ordinarily employed in parallel computer design. The major distinguishing aspects are: (1) a top-down rather than bottom-up design process; (2) the design considers the entire ...
Adams, L. M. +5 more
core +1 more source
Science and Technology of Nuclear Installations, 2012 A general evaluation methodology development and application process (EMDAP) paradigm is described for the resolution of severe accident safety issues.
Robert P. Martin
doaj +1 more source
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source