Results 101 to 110 of about 4,098,484 (351)

Evaluation of the Federal Aviation Administration’s Rigid Airfield Pavement Cracking Failure Models [PDF]

open access: yes, 2021
The Federal Aviation Administration’s (FAA’s) pavement thickness design software, FAA Rigid and Flexible Iterative Elastic Layer Design (FAARFIELD) uses bottom-up fatigue cracking as the only failure criterion in its rigid pavement design procedure ...
Ceylan, Halil   +3 more
core   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Small amphipathic peptides are responsible for the assembly of cruciferin nanoparticles

open access: yesScientific Reports, 2017
Amphipathic peptides are versatile building blocks for fabricating well-ordered nanostructures, which have gained much attention owing to their enormous design possibilities and bio-functionalities.
Hui Hong, Ali Akbari, Jianping Wu
doaj   +1 more source

Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1029-1053, April 2025.
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler   +12 more
wiley   +1 more source

Hypnotic suggestion versus sensory modulation of bodily awareness.

open access: yesPLoS ONE, 2023
Bodily awareness arises from somatosensory, vestibular, and visual inputs but cannot be reduced to these incoming sensory signals. Cognitive factors are known to also impact bodily awareness, though their specific influence is poorly understood.
C Apelian, D B Terhune, F De Vignemont
doaj   +1 more source

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1155-1169, April 2025.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park   +8 more
wiley   +1 more source

THE EFFECT OF USING TOP-DOWN AND BOTTOM-UP STRATEGIES TOWARD STUDENTS’ ABILITY IN COMPREHENDING THE RECORDED NARRATIVE STORY AT THE FIRST YEAR STUDENTS OF MAN 1 PEKANBARU [PDF]

open access: yes, 2012
Listening is one of the basic language skills which plays an important role in communication. In the early days of English Language Teaching (ELT), listening chiefly served as a means of introducing new grammar through model dialogues.
Tito Santana
core  

Saliency-driven system models for cell analysis with deep learning. [PDF]

open access: yes, 2019
Background and objectivesSaliency refers to the visual perception quality that makes objects in a scene to stand out from others and attract attention.
Bianchi, Andrea GC   +8 more
core   +2 more sources

Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1132-1154, April 2025.
PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang   +6 more
wiley   +1 more source

Changing work engagement: The longitudinal effect of a job redesign intervention among public sector employees [PDF]

open access: yesStrategic Management, 2017
Work or employee engagement might be increased through job re-design interventions such as top-down managerial interventions, bottom-up job crafting or bipolar ideals.
Hernaus Tomislav   +2 more
doaj  

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