Results 121 to 130 of about 1,475,669 (329)

Rethinking Agent Design: From Top-Down Workflows to Bottom-Up Skill Evolution

Most LLM-based agent frameworks adopt a top-down philosophy: humans decompose tasks, define workflows, and assign agents to execute each step. While effective on benchmark-style tasks, such systems rely on designer updates and overlook agents' potential to learn from experience.
Du, Jiawei, Wu, Jinlong, Chen, Yuzheng, Hu, Yucheng, Li, Bing, Zhou, Joey Tianyi   +5 more
openaire   +2 more sources

Functional parameters of spermatozoa obtained by a new selection device

FEBS Open Bio, EarlyView.
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez, Paulina Torres, Gabriela Carrasquel‐Martínez, María G. Figueroa‐Méndez, Diana Flores, Lina Villar, Israel Maldonado, Marcela B. Trevino, Claudia Treviño   +8 more
wiley   +1 more source

Paradigm shift from self-assembly to commanded assembly of functional materials: recent examples in porphyrin/fullerene supramolecular systems

Science and Technology of Advanced Materials, 2012
Current nanotechnology based on top-down nanofabrication may encounter a variety of drawbacks in the near future so that development of alternative methods, including the so-called bottom-up approach, has attracted considerable attention.
Mao Li, Shinsuke Ishihara, Qingmin Ji, Misaho Akada, Jonathan P Hill and Katsuhiko Ariga
doaj   +1 more source

Bottom-up vs. top-down: how participatory design can be used to help define post-conflict cultural memory in Croatia [PDF]

, 2023
Antonia Jolic
openalex   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

FEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian, Di Liu, Bing Liu, Yu Lan, Jie Zhou   +4 more
wiley   +1 more source

Pro-Active Regional Development Policy - the Croatian Case [PDF]

, 2003
The paper deals with existing regional development discrepancies in Croatia and discusses possibilities of initiating dormant development potentials and closing development gaps. Bottom up policy approach is analysed in view of Croatian specific regional
Starc, Nenad, Sumpor, Marijana
core  

From Nanofabrication to Self-fabrication – Tailored Chemistry for Control of Single Molecule Electronic Devices

CHIMIA, 2010
Single molecule electronics is a field of research focused on the use of single molecules as electronics components. During the past 15 years the field has concentrated on development of test beds for measurements on single molecules.
Kasper Moth-Poulsen, Thomas Bjørnholm
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Artificial Intelligence for the design of bottom up/Top down of Organizations, funding for sustainable Research and Start-Up developments

, 2023
Lucia V. Gontero Bracamonte, A. Guillermo Bracamonte   +1 more
openalex   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

FEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper, Sridhar Sreeramulu, Benjamin T. Lanham, Elizabeth M. Engle, David Fushman, Harald Schwalbe   +5 more
wiley   +1 more source