Results 131 to 140 of about 4,098,484 (351)

The FEM-2 design method [PDF]

open access: yes
The FEM-2 parallel computer is designed using methods differing from those ordinarily employed in parallel computer design. The major distinguishing aspects are: (1) a top-down rather than bottom-up design process; (2) the design considers the entire ...
Adams, L. M.   +5 more
core   +1 more source

Staff development at RMIT: Bottom‐up work serviced by top‐down investment and policy [PDF]

open access: yes, 2000
Effective staff development is the weaving together of many strands. We need to support staff in their current work, while providing them with ideas, incentives and resources to look for new ways to design learning environments which will enhance student
Kennedy, Paul, McNaught, Carmel
core   +2 more sources

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1436-1451, May 2025.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

From emissions to source allocation: Synergies and trade-offs between top-down and bottom-up information

open access: yesAtmospheric Environment: X, 2020
This study investigates the dispersion of atmospheric pollutants over a coastal region of north-western Italy by means of modelling techniques. A series of annual air quality model simulations corresponding to different emission reduction scenarios has ...
L. Sartini   +3 more
doaj  

Critical success factors of a bottom up urban design process to deliver sustainable urban designs [PDF]

open access: yes
A sustainable urban environment caters for peoples’ need. When the needs of the people are addressed, it increases the property values and attracts investors.
Amaratunga, Dilanthi   +3 more
core  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

CO2 coordination-driven top-down synthesis of a 2D non-layered metal–organic framework

open access: yesFundamental Research, 2022
Combining the physical advantages of two-dimensional (2D) inorganic nanosheets and the modular design and programmed structure of metal-organic frameworks (MOFs), 2D MOFs remain at the forefront of functional material research. Despite tremendous efforts,
Yannan Zhou   +7 more
doaj  

Epithelial Tissues from the Bottom-Up: Contact Inhibition, Wound Healing, and Force Networks [PDF]

open access: yesarXiv
In processes such as embryo shaping, wound healing, and malignant cell invasion, epithelial cells transition between dispersed phases, where the cells move independently, and condensed phases, where they aggregate and deform to close gaps, forming confluent tissues.
arxiv  

Quantum Theory in Design [PDF]

open access: yesarXiv, 2014
In this paper, we use braiding diagrams to present rules of shapes and designs. That is, we design colour, design size, design brightness, design codes by means of braiding.
arxiv  

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