Results 131 to 140 of about 1,548,118 (340)
Characterization of ribosome heterogeneity during endothelial to hematopoietic transition
FEBS Open Bio, EarlyView.The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian +4 more
wiley +1 more source
Rethinking Agent Design: From Top-Down Workflows to Bottom-Up Skill Evolution
Most LLM-based agent frameworks adopt a top-down philosophy: humans decompose tasks, define workflows, and assign agents to execute each step. While effective on benchmark-style tasks, such systems rely on designer updates and overlook agents' potential to learn from experience.
Du, Jiawei +5 more
openaire +2 more sources
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Integrated sleep scheduling for multiple relays and UEs in LTE-TDD
EURASIP Journal on Wireless Communications and Networking, 2019 Energy-saving for the LTE-A network with relay nodes in TDD mode is addressed in this paper, and integrated sleep scheduling schemes for relay nodes and user devices under a base station are designed.
Chun-Chuan Yang +3 more
doaj +1 more source
Bottom-up vs. top-down: how participatory design can be used to help define post-conflict cultural memory in Croatia [PDF]
, 2023 Antonia Jolic
openalex +1 more source
Designing Instructional Materials for Teaching Listening Comprehension [PDF]
, 1988 An approach to the design of listening comprehension materials and classroom activities reflects a view of the nature of listening and the processes it involves.
Richards, Jack
core
Top-down and bottom-up microbiome engineering approaches to enable biomanufacturing from waste biomass. [PDF]
UNLABELLED: Growing environmental concerns and the need to adopt a circular economy have highlighted the importance of waste valorization for resource recovery.
Betenbaugh, Michael +8 more
core +1 more source
FEBS Open Bio, EarlyView.Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper +5 more
wiley +1 more source
Science and Technology of Advanced Materials, 2012 Current nanotechnology based on top-down nanofabrication may encounter a variety of drawbacks in the near future so that development of alternative methods, including the so-called bottom-up approach, has attracted considerable attention.
Mao Li, Shinsuke Ishihara, Qingmin Ji, Misaho Akada, Jonathan P Hill and Katsuhiko Ariga
doaj +1 more source
CD9‐association with PIP2 areas is regulated by a CD9 salt bridge
FEBS Open Bio, EarlyView.The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi +2 more
wiley +1 more source