Results 141 to 150 of about 1,538,506 (330)

Structural synthesis of parallel programs (Methodology and Tools) [PDF]

open access: yesComputer Science Journal of Moldova, 1995
Concepts of structured programming and propositional program logics were anticipated in the systems of algorithmic algebras (SAAs) introduced by V.M.Glushkov in 1965.
G. Cejtlin, E. Jushchenko
doaj  

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam   +6 more
wiley   +1 more source

Storytelling e user led design per rinnovare l’identità dei luoghi [PDF]

open access: yes, 2016
Storytelling and user-led design to renovate places identity Place identity design takes place in a very complex, dialectic and diachronic frame and it faces with problems about the relationship between identity and reputation and those about timing ...
Parente, Marina
core  

Top-Down or Bottom-Up Data Model Design: Which is Best?

open access: yes
AbstractWhen designing an effective enterprise data strategy, organizations often choose between a top-down and a bottom-up approach. Each method has its unique advantages and is suitable for various scenarios. The top-down approach begins with a high-level view of the business needs and strategic objectives, then gradually breaks down this view into ...
openaire   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann   +6 more
wiley   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez   +12 more
wiley   +1 more source

TEACHER’S STRATEGY IN TEACHING DESCRIPTIVE TEXT IN A VOCATIONAL HIGH SCHOOL IN BANDUNG [PDF]

open access: yes, 2016
This research aims to find out how the teacher teaches descriptive text in vocational high school. This research uses case study research design and the subject of this research is a teacher of English in a vocational high school in Bandung.
Sulistya, Puspita Putri
core  

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma   +5 more
wiley   +1 more source

Pro-Active Regional Development Policy - the Croatian Case [PDF]

open access: yes, 2003
The paper deals with existing regional development discrepancies in Croatia and discusses possibilities of initiating dormant development potentials and closing development gaps. Bottom up policy approach is analysed in view of Croatian specific regional
Starc, Nenad, Sumpor, Marijana
core  

Data‐Driven Discovery of Organic Electronic Materials Enabled by Hybrid Top‐Down/Bottom‐Up Design

open access: hybrid, 2023
J. Terence Blaskovits   +3 more
openalex   +1 more source

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