Results 151 to 160 of about 1,548,118 (340)
Storytelling e user led design per rinnovare l’identità dei luoghi [PDF]
, 2016 Storytelling and user-led design to renovate places identity Place identity design takes place in a very complex, dialectic and diachronic frame and it faces with problems about the relationship between identity and reputation and those about timing ...
Parente, Marina
core
Top-Down or Bottom-Up Data Model Design: Which is Best?
AbstractWhen designing an effective enterprise data strategy, organizations often choose between a top-down and a bottom-up approach. Each method has its unique advantages and is suitable for various scenarios. The top-down approach begins with a high-level view of the business needs and strategic objectives, then gradually breaks down this view into ...
openaire +1 more source
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
FEBS Open Bio, EarlyView.Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco +5 more
wiley +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
FEBS Open Bio, EarlyView.A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
Designing Representations, Affecting Reality: A Meta-Model Proposal to Address the Question of Design Epistemology from the Perspective of Cognitive Science [PDF]
Journal of Systemics, Cybernetics and Informatics, 2018 The paper concerns representation intended as abstraction of a model from reality through perception. The relation between reality and its model is a key issue to design because while the project is thought on models, it always affects reality, and this ...
Andrea Zammataro
doaj
Spinal Cord Abnormalities in Early Pediatric Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Spinal cord lesions and atrophy in the cervical region are common in adult multiple sclerosis (MS) and correlate with disability. Whether similar abnormalities occur in pediatric MS patients is largely unknown. Clinical and MRI evaluations were performed in 38 pediatric MS patients and 13 healthy controls (HC).
Monica Margoni +7 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo +11 more
wiley +1 more source
Multi-Scale Face Restoration with Sequential Gating Ensemble Network
, 2018 Restoring face images from distortions is important in face recognition applications and is challenged by multiple scale issues, which is still not well-solved in research area.
Chen, Zhibo +2 more
core +1 more source
TEACHER’S STRATEGY IN TEACHING DESCRIPTIVE TEXT IN A VOCATIONAL HIGH SCHOOL IN BANDUNG [PDF]
, 2016 This research aims to find out how the teacher teaches descriptive text in vocational high school. This research uses case study research design and the subject of this research is a teacher of English in a vocational high school in Bandung.
Sulistya, Puspita Putri
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous neurodegenerative diseases causing progressive deterioration and reduced quality of life. Therapeutic advances have been limited by a lack of sensitive anatomic, functional, or diffusion imaging‐based biomarkers.
David J. Arpin +11 more
wiley +1 more source