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Top-Down Versus Bottom-Up Nanoengineering Routes to Design Advanced Oropharmacological Products
Current Pharmaceutical Design, 2016Energy intensive and chemical routes predominately govern modern dental material fabrication involving complex physicochemical approaches. Current interest in dental material design is shifting towards biomineralization method and green chemistry synthesis to support oral tissue biocompatibility and oropharmacology.
Ajay V, Singh, Krunal K, Mehta
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Trends in Biotechnology, 2020
Biological engineering has unprecedented potential to solve society's most pressing challenges. Engineering approaches must consider complex technical, economic, and social factors. This requires methods that confer gene/pathway-level functionality and organism-level robustness in rapid and cost-effective ways.
Dahabieh, Matthew S. +3 more
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Biological engineering has unprecedented potential to solve society's most pressing challenges. Engineering approaches must consider complex technical, economic, and social factors. This requires methods that confer gene/pathway-level functionality and organism-level robustness in rapid and cost-effective ways.
Dahabieh, Matthew S. +3 more
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Modelling an ongoing design process utilizing top-down and bottom-up design strategies
Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, 2008The product design process plays a central role in ensuring that new products are realized with improved quality, in a short lead-time and with costs kept to a minimum. It is identified that making decisions dynamically on how the design process should proceed is not trivial.
M Fathianathan, J H Panchal
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Bottom-up, Top-down? Connecting Software Architecture Design with Use
2008Participatory design has traditinally focused on the design of technology applications or the co-realisation of a more holostic socio-technical bricolage of new and existing technologies and pratices. 'Infrastructural' design issues like software architectures, programming languages, communication, security, and resource models do not seen to be in ...
Buscher, Monika +4 more
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Ordering effects in nested ‘top-down’ and ‘bottom-up’ contingent valuation designs
Ecological Economics, 2003Abstract Within a contingent valuation (CV) survey ordering effects are defined where responses to a given question vary in a theoretically unanticipated manner according to the positioning of that question relative to others in the survey instrument.
Powe NA, Bateman IJ
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Designing redox metalloproteins from bottom-up and top-down perspectives
Current Opinion in Structural Biology, 2003The design of redox-active metalloproteins has been approached from two different directions. The de novo design approach has recently reached an important stage, at which structural information on several different designed metalloproteins has been obtained. This new information highlights the real challenge of this approach.
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Top-down or bottom-up? – How environmental benchmarks can support the design process
Building and Environment, 2019 Abstract Buildings are responsible for a large share of greenhouse gas (GHG) emissions. The use of Life Cycle Assessment (LCA) during the design phase can help to improve the environmental performance of buildings. However, designers and clients find it difficult to set environmental performance targets and interpret the results obtained through LCA ...
Alexander Hollberg +2 more
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Job Design: From Top-Down Managerial Control to Bottom-Up ‘Job Crafting’
, 2016 openalex +2 more sources
Bottoms Up! Testing Top-Down Software Designs
SAE Technical Paper Series, 1999<div class="htmlview paragraph">Software development schedules are being stretched to the breaking point across the automotive industry, while quality requirements are skyrocketing. Improved specifications help in the development of quality software, but further steps are warranted.</div> <div class="htmlview paragraph">Software ...
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Balancing Participatory Design Approaches in Slum Upgradation: When Top-Down Meets Bottom-Up!
, 2020 The chapter discusses a participatory planning approach utilised for informal (slum) settlement upgradation. A review of approaches identifies the failures of top-down processes and demonstrates the challenges of bottom-up processes. A middle-ground planning approach, where top-down spatial solutions grounded in disciplinary knowledge mesh with the ...
Reena Tiwari +2 more
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