Results 41 to 50 of about 1,475,669 (329)

Multi-skeleton model for top-down design of complex products

Advances in Mechanical Engineering, 2016
Generally, there are two alternative design approaches available to engineers: bottom-up and top-down. Considering the sharp increase in the complexity of most mechanical products, the top-down design approach is more widely adopted in the development of
Dexin Chu, Guolin Lyu, Xuening Chu, Jing Shen   +3 more
doaj   +1 more source

Computer technologies for concrete airfield pavement design

Aviation, 2018
The purpose of the research is to develop formulas, expressions and a computer program for concrete airfield pavement design under the impact of all Airbus 380 main landing gears taking into consideration the design factor of tensile stresses at the top ...
Oleksandr Rodchenko
doaj   +1 more source

Fabrication and Characterization of Double- and Single-Clamped CuO Nanowire Based Nanoelectromechanical Switches

Nanomaterials, 2021
Electrostatically actuated nanoelectromechanical (NEM) switches hold promise for operation with sharply defined ON/OFF states, high ON/OFF current ratio, low OFF state power consumption, and a compact design.
Liga Jasulaneca, Alexander I. Livshits, Raimonds Meija, Jelena Kosmaca, Raitis Sondors, Matiss M. Ramma, Daniels Jevdokimovs, Juris Prikulis, Donats Erts   +8 more
doaj   +1 more source

Towards a Compositional Approach to the Design and Verification of Distributed Systems [PDF]

, 1999
We are investigating a component-based approach for formal design of distributed systems. In this paper, we introduce the framework we use for specification, composition and communication and we apply it to an example that highlights the different ...
Chandy, K. Mani, Charpentier, Michel
core   +6 more sources

Bottom-up or top-down: unit cost estimation of tuberculosis diagnostic tests in India. [PDF]

, 2017
SETTING: Of 18 sites that participated in an implementation study of the Xpert® MTB/RIF assay in India, we selected five microscopy centres and two reference laboratories. OBJECTIVE: To obtain unit costs of diagnostic tests for tuberculosis (TB) and drug-
Boehme, C, Hoog, AH Van't, Khaparde, SD, Nair, SA, Raizada, N, Rupert, S, Sachdeva, KS, Salhotra, VS, Vassall, A   +8 more
core   +1 more source

Networks of silicon nanowires: a large-scale atomistic electronic structure analysis [PDF]

, 2013
Networks of silicon nanowires possess intriguing electronic properties surpassing the predictions based on quantum confinement of individual nanowires.
Bulutay, Ceyhun, Heinig, Karl-Heinz, Keleş, Ümit, Liedke, Bartosz   +3 more
core   +2 more sources

A proposal of method for module commonization in product family (Application of diversity analysis method to servo motors and verification of its effectiveness)

Nihon Kikai Gakkai ronbunshu
A method for both quality improvement and design efficiency is required to meet diversifying customer requirements and human resource development. Especially in the case of production approach with customization, such as in industrial equipment, a design
Naoki INOUE, Kenichi SAGAYAMA, Kenta SUMA, Takashi KOBAYASHI, Kenichi WAKITA, Takehiro NAKAI, Yoshiki MAEDA, Kazuki MASUDA, Fumiaki TSUCHIYA   +8 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source