Results 61 to 70 of about 1,548,118 (340)
Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
FEBS Letters, EarlyView.The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai +2 more
wiley +1 more source
CO2 coordination-driven top-down synthesis of a 2D non-layered metal–organic framework
Fundamental Research, 2022 Combining the physical advantages of two-dimensional (2D) inorganic nanosheets and the modular design and programmed structure of metal-organic frameworks (MOFs), 2D MOFs remain at the forefront of functional material research. Despite tremendous efforts,
Yannan Zhou +7 more
doaj +1 more source
Reflecting on the usability of research on culture in designing interaction [PDF]
, 2010 The concept of culture has been attractive to producers of interactive\ud systems who are willing to design useful and relevant solutions to users\ud increasingly located in culturally diverse contexts.
Camara, Souleymane +1 more
core +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Re‐considering and designing microbiomes for future waste biorefinery
Microbial BiotechnologyIt is an increasingly promising research direction using microbiomes to produce various chemicals in order to support people's growing need for sustainability.
Menghan Wu, Hui Wang
doaj +1 more source
BuildingsThe selection of an appropriate construction method stands as a pivotal decision in ensuring the success of any building project. This paper undertakes a comprehensive comparative analysis of cost and timeline implications between the top-down and bottom-
Çetin Meral +2 more
doaj +1 more source
MasterChem: Cooking 2D-polymers [PDF]
, 2016 2D-polymers are still dominated by graphene and closely related materials such as boron nitride, transition metal sulphides and oxides. However, the rational combination of molecules with suitable design is already showing the high potential of chemistry
Amo-Ochoa, P. +2 more
core +2 more sources
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
Bottom-up and Top-down: Bidirectional Additive Net for Edge Detection
International Joint Conference on Artificial Intelligence, 2020 Image edge detection is considered as a cornerstone task in computer vision. Due to the nature of hierarchical representations learned in CNN, it is intuitive to design side networks utilizing the richer convolutional features to improve the edge ...
Lianli Gao +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source