Results 71 to 80 of about 1,475,669 (329)

Learning to design for social sustainability through the synthesis of two approaches [PDF]

open access: yes, 2013
This paper brings together research that I was involved in the SUE –MOT (sustainable urban environments; metrics models and toolkits) funded by the EPSRC (completed in 2010) and my work in Sri Lanka on a pioneering project to relocate Canal Bank dwellers
Paranagamage, Primali
core  

New bottom-up algorithm for assembly plan generation : opportunities for micro-factory design. [PDF]

open access: yes, 2007
International audienceThis paper discusses a new approach dedicated to assembly plan generation, called "bottom-up algorithm". It is compared to the traditional "top-down approach", usually used to perform this stage of the design process of the assembly
Lutz, Philippe   +2 more
core   +2 more sources

How can impact strategies be developed that better support universities to address twenty-first-century challenges?

open access: yesResearch for All, 2022
To better address twenty-first-century challenges, research institutions often develop and publish research impact strategies, but as a tool, impact strategies are poorly understood.
doaj   +2 more sources

Bottom-Up Design Approach for OBOC Peptide Libraries

open access: yesMolecules, 2020
One-bead-one-compound peptide libraries, developed following the top-down experimental approach, have attracted great interest in the identification of potential ligands or active peptides.
Daniela Kalafatovic   +3 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

STUDENTS’ READING STRATEGIES AT ENGLISH EDUCATIONAL DEPARTMENT

open access: yesAl-Ishlah: Jurnal Pendidikan, 2019
Reading comprehension is one of the skills that students must have to enrich their knowledge, especially university students. There are two kinds of reading strategies: Top – Down strategy and Bottom – Up Strategy.
Utami Dewi, Maryati Salmiah
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

The Facets of Place [PDF]

open access: yes, 1996
This chapter will outline one theory aimed at integrating aspects of environmental psychology with issues in architectural design. The theory to be reviewed is broad in those characteristics of theory that Moore (1987) called their 'form and scope ...
Canter, David V.
core  

Citizen centered design

open access: yesIn_Bo, 2015
Today architecture has to design for rapidly changing futures, in a citizen-centered way. That is, architecture needs to embrace meaningful design. Societal challenges ask for a new paradigm in city-making, which combines top-down public management with ...
Ingrid Mulder
doaj   +1 more source

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