Results 81 to 90 of about 1,562,665 (304)
Changes in electrophysiological markers of cognitive control after administration of galantamine
NeuroImage: Clinical, 2018 The healthy brain is able to maintain a stable balance between bottom-up sensory processing and top-down cognitive control. The neurotransmitter acetylcholine plays a substantial role in this.
Lauren E. Gascoyne +9 more
doaj +1 more source
Critical success factors of a bottom up urban design process to deliver sustainable urban designs [PDF]
A sustainable urban environment caters for peoples’ need. When the needs of the people are addressed, it increases the property values and attracts investors.
Amaratunga, Dilanthi +3 more
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Evolving Symbolic Controllers [PDF]
, 2003 International audienceThe idea of symbolic controllers tries to bridge the gap between the top-down manual design of the controller architecture, as advocated in Brooks' subsumption architecture, and the bottom-up designer-free approach that is now ...
D. Floreano +5 more
core +3 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Assessing the design of integrated methane sensing networks
Environmental Research LettersWhile methane is the second largest contributor to global warming after carbon dioxide, it has a larger warming effect over a much shorter lifetime. Despite accelerated technological efforts to radically reduce global carbon dioxide emissions, rapid ...
Lekha Patel, Jake P Zenker
doaj +1 more source
Data-driven discovery of organic electronic materials enabled by hybrid top-down/bottom-up design [PDF]
, 2022 Rubén Laplaza +3 more
openalex +1 more source
Ab initio Computational Study of Quantum Plasmons in Graphene Nanoflakes [PDF]
, 2017 We investigate the potential merit in using nanometer-sized graphene flakes as building blocks of twodimensional (2D) quantum metamaterials. The choice of the building blocks is crucial to the design of quantum metamaterials with desired properties ...
Manrique, DZ, Panoiu, NC
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New bottom-up algorithm for assembly plan generation : opportunities for micro-factory design. [PDF]
, 2007 International audienceThis paper discusses a new approach dedicated to assembly plan generation, called "bottom-up algorithm". It is compared to the traditional "top-down approach", usually used to perform this stage of the design process of the assembly
Lutz, Philippe +2 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Aligning capital with risk [PDF]
, 2015 The interaction of capital and risk is of primary interest in the corporate governance of banks as it links operational profitability and strategic risk management.
Ebnöther, Silvan, Trojani, Fabio
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