Results 81 to 90 of about 1,548,118 (340)

Networks of silicon nanowires: a large-scale atomistic electronic structure analysis [PDF]

, 2013
Networks of silicon nanowires possess intriguing electronic properties surpassing the predictions based on quantum confinement of individual nanowires.
Bulutay, Ceyhun, Heinig, Karl-Heinz, Keleş, Ümit, Liedke, Bartosz   +3 more
core   +2 more sources

Bottom-Up and Top-Down Neural Processing Systems Design: Neuromorphic Intelligence as the Convergence of Natural and Artificial Intelligence

, 2021
While Moore's law has driven exponential computing power expectations, its nearing end calls for new avenues for improving the overall system performance. One of these avenues is the exploration of new alternative brain-inspired computing architectures that promise to achieve the flexibility and computational efficiency of biological neural processing ...
Frenkel, Charlotte Philippine, Bol, David, Indiveri, Giacomo   +2 more
openaire   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Saliency-driven system models for cell analysis with deep learning. [PDF]

, 2019
Background and objectivesSaliency refers to the visual perception quality that makes objects in a scene to stand out from others and attract attention.
Bianchi, Andrea GC, Carneiro, Cláudia M, Ferreira, Daniel S, Medeiros, Fátima NS, Ramalho, Geraldo LB, Rezende, Mariana T, Tobias, Alessandra HG, Torres, Débora, Ushizima, Daniela M   +8 more
core   +2 more sources

What is Normalization? The Strategies Employed in Top-Down and Bottom-Up Proteome Analysis Workflows

Proteomes, 2019
The accurate quantification of changes in the abundance of proteins is one of the main applications of proteomics. The maintenance of accuracy can be affected by bias and error that can occur at many points in the experimental process, and normalization ...
Matthew B. O’Rourke, S. E. Town, Penelope V Dalla, Fiona Bicknell, Naomi Koh Belic, Jake P. Violi, J. R. Steele, M. Padula   +7 more
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

How can impact strategies be developed that better support universities to address twenty-first-century challenges?

Research for All, 2022
To better address twenty-first-century challenges, research institutions often develop and publish research impact strategies, but as a tool, impact strategies are poorly understood.
doaj   +2 more sources

Bottom-Up Design Approach for OBOC Peptide Libraries

Molecules, 2020
One-bead-one-compound peptide libraries, developed following the top-down experimental approach, have attracted great interest in the identification of potential ligands or active peptides.
Daniela Kalafatovic, Goran Mauša, Dina Rešetar Maslov, Ernest Giralt   +3 more
doaj   +1 more source

Integrating top–down and bottom–up approaches to design a new framework to assess crop diversification sustainability

, 2019
Christian Bockstaller
openalex   +3 more sources

Decentralized provenance-aware publishing with nanopublications [PDF]

, 2016
Publication and archival of scientific results is still commonly considered the responsability of classical publishing companies. Classical forms of publishing, however, which center around printed narrative articles, no longer seem well-suited in the ...
Chichester, Christine, Dumontier, Michel, Giannakopoulos, George, Krauthammer, Michael, Kuhn, Tobias, Ngonga Ngomo, Axel-Cyrille, Queralt-Rosinach, Núria, Verborgh, Ruben, Viglianti, Raffaele   +8 more
core   +4 more sources