Results 81 to 90 of about 1,475,669 (329)

Robust top-down and bottom-up visual saliency for mobile robots using bio-inspired design principles [PDF]

open access: green, 2021
Uziel Jaramillo-Avila   +3 more
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Development of Neural Electromagnetic Ontologies (NEMO): Ontology-based Tools for Representation and Integration of Event-related Brain Potentials [PDF]

open access: yes, 2009
We describe a first-generation ontology for representation and integration of event-related brain potentials (ERPs). The ontology is designed following OBO “best practices” and is augmented with tools to perform ontology-based ...
Dejing Dou   +4 more
core   +3 more sources

Computer-aided design of nano-filter construction using DNA self-assembly

open access: yesNanoscale Research Letters, 2006
Computer-aided design plays a fundamental role in both top-down and bottom-up nano-system fabrication. This paper presents a bottom-up nano-filter patterning process based on DNA self-assembly.
Mohammadzadegan Reza, Mohabatkar Hassan
doaj   +1 more source

Small amphipathic peptides are responsible for the assembly of cruciferin nanoparticles

open access: yesScientific Reports, 2017
Amphipathic peptides are versatile building blocks for fabricating well-ordered nanostructures, which have gained much attention owing to their enormous design possibilities and bio-functionalities.
Hui Hong, Ali Akbari, Jianping Wu
doaj   +1 more source

Hypnotic suggestion versus sensory modulation of bodily awareness.

open access: yesPLoS ONE, 2023
Bodily awareness arises from somatosensory, vestibular, and visual inputs but cannot be reduced to these incoming sensory signals. Cognitive factors are known to also impact bodily awareness, though their specific influence is poorly understood.
C Apelian, D B Terhune, F De Vignemont
doaj   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Top-down and bottom-up microbiome engineering approaches to enable biomanufacturing from waste biomass. [PDF]

open access: yes
UNLABELLED: Growing environmental concerns and the need to adopt a circular economy have highlighted the importance of waste valorization for resource recovery.
Betenbaugh, Michael   +8 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

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