Results 191 to 200 of about 228,482 (264)

Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells

open access: yesCell Proliferation, EarlyView.
hESCsdel18q exhibit delayed and impaired anterior neuroectoderm induction, leading to deficient RPE specification. hESCsdel18q lines showed dysregulation of TGFβ signalling, and endogenous overactivation of activin/nodal/TGFβ in hESCsdel18q leads to improper anterior/posterior neuroectodermal fate commitments.
Yingnan Lei   +9 more
wiley   +1 more source

Mesial‐to‐lateral gradients of epileptiform activity to localize mesial temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Mesial temporal lobe epilepsy is a common localization of drug‐resistant epilepsy in adults. Patients often undergo intracranial electroencephalographic monitoring to confirm localization and determine candidacy for focal ablation or resection. Clinicians primarily base surgical decision‐making on seizure onset patterns, with imaging
Carlos A. Aguila   +16 more
wiley   +1 more source

Extracting epilepsy‐related information from unstructured clinic letters using large language models

open access: yesEpilepsia, EarlyView.
Abstract Objective The emergence of large language models (LLMs) and the increasing prevalence of electronic health records (EHRs) present significant opportunities for advancing health care research and practice. However, research that compares and applies LLMs to extract key epilepsy‐related information from unstructured medical free text is under ...
Shichao Fang   +7 more
wiley   +1 more source

From Data Deficient to Big Data in Shark Conservation

open access: yesFish and Fisheries, EarlyView.
ABSTRACT Citizen science is increasingly harnessed worldwide to gather data otherwise requiring a prohibitive investment of funding and time. Meanwhile, the revolution in digital communication offers opportunities from crowdsourcing, big data approaches and social network mining to quickly and cost‐effectively fill major gaps in knowledge necessary to ...
F. Ferretti   +8 more
wiley   +1 more source

Enhanced semantic classification of microbiome sample origins using Large Language Models (LLMs)

open access: yes
Gaio D   +6 more
europepmc   +1 more source

Dedicated AI Expert System vs Generative AI With Large Language Model for Clinical Diagnoses.

open access: yesJAMA Netw Open
Feldman MJ   +8 more
europepmc   +1 more source

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