Results 61 to 70 of about 227,245 (293)

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

open access: yesAdvanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu   +19 more
wiley   +1 more source

A Minimal Span-Based Neural Constituency Parser

open access: yes, 2017
In this work, we present a minimal neural model for constituency parsing based on independent scoring of labels and spans. We show that this model is not only compatible with classical dynamic programming techniques, but also admits a novel greedy top ...
Andreas, Jacob   +2 more
core   +1 more source

ProteoSeeker: A Feature‐Rich Metagenomic Analysis Tool for Accessible and Comprehensive Metagenomic Exploration

open access: yesAdvanced Science, EarlyView.
ProteoSeeker is a new metagenomic analysis tool that accelerates protein discovery. By automating key steps, it reduces computational complexity and enables comprehensive dataset analysis, performing protein identification, screening based on user‐defined protein families, and taxonomic analysis.
Georgios Filis   +6 more
wiley   +1 more source

A Survey of Unsupervised Dependency Parsing [PDF]

open access: yesarXiv, 2020
Syntactic dependency parsing is an important task in natural language processing. Unsupervised dependency parsing aims to learn a dependency parser from sentences that have no annotation of their correct parse trees. Despite its difficulty, unsupervised parsing is an interesting research direction because of its capability of utilizing almost unlimited
arxiv  

Optimal LZ-End Parsing is Hard [PDF]

open access: yesarXiv, 2023
LZ-End is a variant of the well-known Lempel-Ziv parsing family such that each phrase of the parsing has a previous occurrence, with the additional constraint that the previous occurrence must end at the end of a previous phrase. LZ-End was initially proposed as a greedy parsing, where each phrase is determined greedily from left to right, as the ...
arxiv  

Autonomous Self‐Evolving Research on Biomedical Data: The DREAM Paradigm

open access: yesAdvanced Science, EarlyView.
DREAM is a fully autonomous, self‐evolving biomedical research system capable of independently formulating scientific questions, performing analyses, and making new discoveries without human intervention. Validated in biomedical studies, DREAM significantly outperforms human scientists in research efficiency, accelerating scientific discovery and ...
Luojia Deng   +3 more
wiley   +1 more source

A multirobot system for autonomous deployment and recovery of a blade crawler for operations and maintenance of offshore wind turbine blades

open access: yesJournal of Field Robotics, Volume 40, Issue 1, Page 73-93, January 2023., 2023
Abstract Offshore wind farms will play a vital role in the global ambition of net zero energy generation. Future offshore wind farms will be larger and further from the coast, meaning that traditional human‐based operations and maintenance approaches will become infeasible due to safety, cost, and skills shortages.
Zhengyi Jiang   +7 more
wiley   +1 more source

Active Field Theories [PDF]

open access: yesarXiv, 2019
Lecture Notes for Les Houches 2018 Summer School on Active Matter and Nonequilibrium Statistical Physics. These notes give an introduction to statistical field theories of active matter. After showing an example of how such theories can be created bottom-up by explicit coarse graining of active particle models, the main approach taken here is top-down:
arxiv  

High‐Efficiency Optoelectronic Modulation in Quasi‐2D Perovskite‐Based Transistors for Neuromorphic Computing

open access: yesAdvanced Electronic Materials, EarlyView.
2‐thiophenemethylammonium (ThMA+) spacer cation‐based quasi‐2D (ThMA)2(MA)n‐1PbnI3n+1 (n = 4) photoelectric field‐effect transistors are developed, and its optoelectronic performance and neuromorphic computing are explored. Abstract Optoelectronic modulated transistors based on organic–inorganic halide perovskites can perceive and parse visual ...
Wenwen Wang   +6 more
wiley   +1 more source

Science class as clinic: Why histories of segregated instruction matter for health equity reforms today

open access: yesScience Education, Volume 107, Issue 1, Page 42-70, January 2023., 2023
Abstract Research has recommended centering health disparities to make science instruction relevant to students from minoritized racial and ethnic groups. While promoted as a recent innovation, the repurposing of science instruction to improve the health of demographic groups has a longer history traceable to segregated and colonial schooling.
Kathryn L. Kirchgasler
wiley   +1 more source

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