Results 221 to 230 of about 1,898,707 (253)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Top Management Team and Middle Managers Making Sense of Leadership. [PDF]

Raes, A., Heijltjes, M., Roe, R.A., Glunk, U.   +3 more
core  

Here today, gone tomorrow? Managerial perceptions of opportunities and challenges with temporary employment in eldercare. [PDF]

BMC Health Serv Res
Lindmark T, Hallman D, Bergström G, Strömberg A.   +3 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Ethnic disparities in the longer-term clinical care and outcomes of stroke patients in England. [PDF]

PLoS One
Tang EYH, Anyanwagu U, Fu Y, Price C, SSNAP Collaboration.   +4 more
europepmc   +1 more source

The Experiences and Perceptions of Organizational Support Among Chinese Nurses Following Work-Related Musculoskeletal Disorders: A Qualitative Descriptive Study. [PDF]

Nurs Open
Sunzi K, Lin Y, Huang Q, Guo L, Yang Z, Li F, Zhou W, Lei C.   +7 more
europepmc   +1 more source

Factors Influencing Intention to Leave Among Nurse Managers: A Cross-Sectional Study. [PDF]

Worldviews Evid Based Nurs
Simonetti V, Franconi I, Piermattei N, Faragalli A, Fioretti M, Rossolini D, Santamaria G, Gesuita R, Cicolini G.   +8 more
europepmc   +1 more source

Tips & Trends d. monatl. Informationsdienst von Manager-Magazin

, 1987

core