Results 41 to 50 of about 1,898,707 (253)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

SUCCESSFUL HR AUDIT: IS IT DETERMINED BY TOP MANAGEMENT COMMITMENT, HR CONSULTANTS, AND LINE MANAGER INVOLVEMENT

open access: yesJurnal Manajemen dan Wirausaha, 2022
The research aimed to find out how to execute a successful HR audit by looking into the top ma­na­gement's commitment, HR consultants' function in the business, and the line manager's level of participation in the audit.
Fredson Kotamena   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Psicodinámica del trabajo y análisis del trabajo de «presentación de sí mismo» del director de empresa

open access: yesLaboreal, 2011
Is the psychodynamics of work a relevant theoretical reference for analyzing the work of the top manager and the effects of this work on their subjectivity?
Marisa Wolf-Ridgway
doaj  

Span of Control in Teamwork and Organization Structure [PDF]

open access: yesMontenegrin Journal of Economics, 2018
The span of control expresses how many subordinates correspond to one manager, while determined by many factors and unable to be expanded indefinitely.
Katarina Remenova   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A new leadership model for post-Covid training: the generative manager. [PDF]

open access: yes, 2023
openL’argomento del presente elaborato è il modello del Manager generativo, teorizzato da Paola Pirri, David Cariani e Lara Cesari, psicoterapeuti e psicologi del lavoro e delle organizzazioni.
MASINA, SOFIA
core  

The Issue of Responsibility and Efficiency in the Concept of Top Manager Lifestyle [PDF]

open access: yesJournal on Efficiency and Responsibility in Education and Science, 2009
The article focuses on the top manager lifestyle. The author describes a structure of time allocation by a top manager to individual activities in both professional area and non-work activities it in the context of responsibility towards himself/herself,
Staňková Dana Maria
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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