Results 51 to 60 of about 183,141 (308)

Tevatron top physics [PDF]

open access: yesProceedings of Physics at LHC 2008 — PoS(2008LHC), 2010
7 pages, 3 figures, proceedings of LHC08 ...
openaire   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Search for t t ¯ H $$ \mathrm{t}\overline{\mathrm{t}}\mathrm{H} $$ production in the H → b b ¯ $$ \mathrm{H}\to \mathrm{b}\overline{\mathrm{b}} $$ decay channel with leptonic t t ¯ $$ \mathrm{t}\overline{\mathrm{t}} $$ decays in proton-proton collisions at s = 13 $$ \sqrt{s}=13 $$ TeV

open access: yesJournal of High Energy Physics, 2019
A search is presented for the associated production of a standard model Higgs boson with a top quark-antiquark pair ( t t ¯ H $$ \mathrm{t}\overline{\mathrm{t}}\mathrm{H} $$ ), in which the Higgs boson decays into a b quark-antiquark pair, in proton ...
The CMS collaboration   +2301 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Search for tt¯H $$ \mathrm{t}\overline{\mathrm{t}}\mathrm{H} $$ production in the all-jet final state in proton-proton collisions at s=13 $$ \sqrt{s}=13 $$ TeV

open access: yesJournal of High Energy Physics, 2018
A search is presented for the associated production of a Higgs boson with a top quark pair in the all-jet final state. Events containing seven or more jets are selected from a sample of proton-proton collisions at s=13 $$ \sqrt{s}=13 $$ TeV collected ...
The CMS collaboration   +2301 more
doaj   +1 more source

Measurement of the inclusive and differential t t ¯ $$ \overline{t} $$ γ cross sections in the dilepton channel and effective field theory interpretation in proton-proton collisions at s $$ \sqrt{s} $$ = 13 TeV

open access: yesJournal of High Energy Physics, 2022
The production cross section of a top quark pair in association with a photon is measured in proton-proton collisions in the decay channel with two oppositely charged leptons (e ± μ ∓, e + e − , or μ + μ − ).
The CMS collaboration   +2344 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Boosted Top Quarks, Top Pair Resonances, and Top Partner Searches at the LHC

open access: yesEPJ Web of Conferences, 2013
The increased center-of-mass energy of proton-proton collisions at the LHC allows for higher and higher mass scales to be probed in the search for new physics. These searches for new physics can often involve the reconstruction of top quark decays.
Pilot Justin
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

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