Results 41 to 50 of about 1,611,945 (272)

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

open access: yesFEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka   +6 more
wiley   +1 more source

A Cross-Platform Personalized Recommender System for Connecting E-Commerce and Social Network

open access: yesFuture Internet, 2022
In this paper, we build a recommender system for a new study area: social commerce, which combines rich information about social network users and products on an e-commerce platform.
Jiaxu Zhao   +3 more
doaj   +1 more source

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

The Combination of Contextualized Topic Model and MPNet for User Feedback Topic Modeling

open access: yesIEEE Access, 2023
In the era of big data and ubiquitous internet connectivity, user feedback data plays a crucial role in product development and improvement. However, extracting valuable insights from the vast pool of unstructured text data found in user feedback ...
Mohammad Hamid Asnawi   +3 more
doaj   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Characterizing News Report of the Substandard Vaccine Case of Changchun Changsheng in China: A Text Mining Approach

open access: yesVaccines, 2020
Background: The substandard vaccine case of that broke out in July 2018 in China triggered an outburst of news reports both domestically and aboard. Distilling the abundant textual information is helpful for a better understanding of the character during
Ping Zhou   +3 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Investigating topic modeling techniques through evaluation of topics discovered in short texts data across diverse domains

open access: yesScientific Reports
The online channel has affected many facets of an individual's identity, commercial, social policy, and culture, among others. It implies that discovering the topics on which these brief writings are focused, as well as examining the qualities of these ...
R. Muthusami   +5 more
doaj   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Neural Topic Modeling with Deep Mutual Information Estimation [PDF]

open access: yesarXiv, 2022
The emerging neural topic models make topic modeling more easily adaptable and extendable in unsupervised text mining. However, the existing neural topic models is difficult to retain representative information of the documents within the learnt topic representation.
arxiv  

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