Results 221 to 230 of about 988,863 (326)

Mapping interconnectivity of digital twin healthcare research themes through structural topic modeling. [PDF]

Sci Rep
Kim EM, Lim Y.
europepmc   +1 more source

Using Topic Generation Model to explore the French Parliamentary Debates during the early Third Republic (1881-1899)

, 2022
Nicolas Bourgeois, Aurélien Pellet, Marie Puren   +2 more
openalex   +1 more source

HCET: Hierarchical Clinical Embedding With Topic Modeling on Electronic Health Records for Predicting Future Depression

, 2020
Yiwen Meng, William Speier, Michael Ong, Corey Arnold   +3 more
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Topic modeling and evolutionary trends of China's language policy: A LDA-ARIMA approach. [PDF]

PLoS One
Li T, Ke X, Shi H.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Predicting patient enrollment in a telephone-based principal care management service using topic modeling. [PDF]

PLOS Digit Health
Rus AMM, Ivy JS, Chi M, Plyler M, Wells-Gray E, Mayorga ME.   +5 more
europepmc   +1 more source

Neural Topic Modelling

2019 Conference on Cognitive Computational Neuroscience, 2019
Pamela Hathway, Dan F.M. Goodman
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Exploring the Determinants of Patient Experiences Using the Digital Topic Modeling Approach. [PDF]

J Nurs Manag
Yu X, Huang H, Lin K, Wang H, Zheng S, Ran X, Liu Y, Wu H.   +7 more
europepmc   +1 more source