Results 101 to 110 of about 877,176 (283)

Transungual Delivery of Ciclopirox Is Increased 3–4-Fold by Mechanical Fenestration of Human Nail Plate in an In Vitro Model

Pharmaceutics, 2019
Onychomycosis is a fungal infection of nails that is widespread and difficult to treat because of the impermeable nature of human nails. Topically applied anti-fungal agents cannot penetrate this structure, and treatment regimens often resort to systemic
Damian Cordoba Díaz, Marta Elena Losa Iglesias, Ricardo Becerro de Bengoa Vallejo, Manuel Cordoba Diaz   +3 more
doaj   +1 more source

Topical imiquimod

Journal of Dermatological Treatment, 2001
In this ever-expanding world of immunologic advancements, Drs Langley and Pearson have undertaken this timely, succinct review of imiquimod. Given its direct actions on monocytes and macrophages, as well as the many diverse cytokine effects that follow from these events, topical imiquimod has already solidly established itself as a successful treatment
G W, Pearson, R G, Langley
openaire   +2 more sources

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Summary Talk at the 3rd KEK Topical Conference on CP Violation

, 1994
A summary of the contributions to this topical conference is presented. The topics discussed ranged from detailing what we know about CP violation, to what we hope to learn in the future, to still unsolved mysteries in the subject.Comment: 12 pages, UCLA/
't Hooft, Adler, Altarelli, Baluni, Barr, Barr, Bell, Bigi, Bochkarev, Cabibbo, Callan, Crewther, Cronin, Dine, Farrar, Flynn, Gilman, Grinstein, Gronau, Gronau, Gronau, Guberina, Hikasa, Hikasa, Isgur, Jackiw, Jarlskog, Kobayashi, Kobzarev, Kuzmin, Kuzmin, London, Manohar, Martinelli, Mori, Nelson, Neubert, Nir, Peccei, Peccei, Peccei, Peccei, R.D. Peccei, Sakharov, Samuel, Shabalin, Steigman, Winstein, Wolfenstein   +48 more
core   +2 more sources

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology

Cell Death Discovery
A new type of nonapoptotic, iron-dependent cell death induced by lipid peroxidation is known as ferroptosis. Numerous pathological processes, including inflammation and cancer, have been demonstrated to be influenced by changes in the ferroptosis ...
Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu   +6 more
doaj   +1 more source

Rare region effects at classical, quantum, and non-equilibrium phase transitions

, 2006
Rare regions, i.e., rare large spatial disorder fluctuations, can dramatically change the properties of a phase transition in a quenched disordered system.
Alet F Walczak A M Fisher M P A, Andreichenko V B, Barber M N, Behre J, Berche B, Bergstresser T K, Bramson M, Bray A J, Cardy J, Cardy J, Chopard B, Colborne S G W, Dagotto E, Dhar D, Dhar D, Dickison M, Dickman R, Dorovgotsev S N, Dorovgotsev S N, Dotsenko V, Dotsenko V, Dotsenko V S, Fedorenko A A, Fendler B, Goldenfeld N, Grassberger P, Grinstein G, Harris A B, Harris T E, Hertz J, Jain S, Jensen I, Joyce G S, Landau L D, Landau L D, Landau L D, Landau L D, Larkin A I, Larkin A I, Lifshitz I M, Lifshitz I M, Lifshitz I M, Lin Y C, Lloyd R G, Ma S K, Marro J, Mayer I O, Menyhard N, Miranda E, Obukhov S P, Obukhov S P, Sachdev S, Sachdev S Vojta M Fokas A, Schehr G Rieger H, Schmittmann B, Sinai Y G, Stauffer D, Tauber U C, Thomas Vojta, Todo S, Vafek O Beasley M R Kivelson S A, van der Waals J D, Vojta T, Weiss P   +63 more
core   +1 more source

Topical Analgesics

Brazilian Journal of Anesthesiology, 2012
Pain treatment involves the usage of common and opioid analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs) and adjuvant analgesics. Traditionally, these drugs are administered systemically or into the neuraxis. However, when analgesics are applied through these pathways, they are associated with significant side effects, which can hinder its use.
Flores, Murilo Pereira, de Castro, Anita Perpetua Carvalho Rocha, Nascimento, Jedson dos Santos   +2 more
openaire   +2 more sources

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, in collaboration with the Consensus Expert Panel (CEP) members, G. Alden Adkins, Brittany Adler, Hossein Ansari, Senada Arabelovic, Alan Baer, Denis Balaban, Shamik Bhattacharyya, Evelyn Bromet, Krishna Chaganti, Kamal Chemali, Melissa Cortez, Schartess Culpepper, Paul Dellaripa, Dana Direnzo, Daniel El Bogdadi, Robert Fearon, Mehrnez Fischbach, Judi Furlong, Christopher Gibbons, Rachael Gordon, Thomas Grader Beck, Syed Haider, Larry Hollenbeck, Chadwick R. Johr, Stuart S. Kassan, Brian King, Octavia Kincaid, Eugene Kissin, Vasileios Kyttaris, Lindsay Lally, Brandon M. Law, Janet Lewis, Scott M. Lieberman, Amanda Lusa, Joseph Lutt, Rashmi Maganti, Arthur M. Mandelin, Sara McCoy, Kerry Neall, Timothy Niewold, Anne Louise Oaklander, Ruben A. Peredo‐Wende, Lynn Petruzzi, Mark A. Porter, Guada Respicio Duque, Tania Reyna, Nathaniel M. Robbins, Elliot D. Rosenstein, Laura Rosow, Breanna Ruthrauff, Amit Sachdev, Nora Sandorfi, Sarah Schafer, Elena Schiopu, Chokkalingam Siva, Daniel Small, Sara M. Stern, Lauren Stiles, Susan Stoddard, Jinny Tavee, Donald Thomas, Edward L. Treadwell, Nagagopal Venna, Steven Vernino, Frederick B. Vivino, Brittany Weber, Sepideh Yadollahi, Huiying Yu, Scott Zashin   +88 more
wiley   +1 more source