Results 301 to 310 of about 651,073 (343)

Baricitinib in patients with moderate‐to‐severe atopic dermatitis and inadequate response to topical corticosteroids: results from two randomized monotherapy phase III trials

British Journal of Dermatology, 2020
Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, effectively reduced atopic dermatitis (AD) severity in a phase II study with concomitant topical corticosteroids.
E. Simpson, J. Lacour, L. Spelman, R. Galimberti, L. Eichenfield, R. Bissonnette, B. King, J. Thyssen, J. Silverberg, T. Bieber, K. Kabashima, Y. Tsunemi, A. Costanzo, E. Guttman‐Yassky, L. Beck, J. Janes, A. DeLozier, M. Gamalo, D. Brinker, T. Cardillo, F. Nunes, A. Paller, A. Wollenberg, K. Reich   +23 more
semanticscholar   +1 more source

SLN and NLC for topical, dermal, and transdermal drug delivery

Expert Opinion on Drug Delivery, 2020
Introduction From a biopharmaceutical standpoint, the skin is recognized as an interesting route for drug delivery. In general, small molecules are able to penetrate the stratum corneum, the outermost layer of the skin.
E. Souto, Iara Baldim, W. P. Oliveira, R. Rao, N. Yadav, F. M. Gama, S. Mahant   +6 more
semanticscholar   +1 more source

Topics and topicalization in Amharic

jall, 2007
Abstract The paper examines the information structure of Amharic sentences with regard to topicalization. The morphemes -mma, -ss, and -mm in Amharic have been ascribed a function as topic markers (cf. Blejer 1986, Gasser 1983, Hetzron 1973, Kapeliuk 1978, Leslau 1995, etc.).
Girma A. Demeke, Ronny Meyer
openaire   +2 more sources

Topic- and focus-topicalizations

The Linguistic Review, 1998
In this paper I claim that topic-topicalization is an obligatory substitution movement into Muller and Sternefeld's (1993) Topic Phrase, and that focus-topicalization is an optional adjunction movement to the IP-adjoined position. The present analysis of topic- and focus-topicalizations, coupled with Rizzi's (1990) Relativized Minimality, is shown to ...
openaire   +2 more sources

Topical Microbicides Become Topical

New England Journal of Medicine, 2005
A recent study performed with the use of a nonhuman primate model of sexual transmission suggests that it may be possible for topical microbicides to halt the transmission of HIV-1.
openaire   +3 more sources

Cutaneous candidiasis – an evidence‐based review of topical and systemic treatments to inform clinical practice

Journal of the European Academy of Dermatology and Venereology, 2019
Cutaneous candidiasis is a common skin disease, and several treatments have been investigated within the last fifty years. Yet, systematic reviews are lacking, and evidence‐based topical and systemic treatment strategies remain unclear.
E. Taudorf, G. Jemec, R. Hay, D. Saunte
semanticscholar   +1 more source

Topical ketoconazole: a systematic review of current dermatological applications and future developments

Journal of dermatological treatment (Print), 2019
Introduction: Although labeling changes and market withdrawal have been implemented for oral ketoconazole (KTZ) due to serious adverse effects (AEs), topical KTZ is generally thought to be effective and safe for the treatment of superficial fungal ...
Franchesca Choi, M. Juhász, N. Atanaskova Mesinkovska   +2 more
semanticscholar   +1 more source