Results 111 to 120 of about 28,018 (262)

Topiramate Adjunctive Therapy for Partial Seizures

open access: yes, 1999
The efficacy and safety of topiramate (TPM) (6 mg/kg/day) in children age 2 to 16 years, as adjunctive therapy for uncontrolled partial-onset seizures (75% complex partial), with or without secondarily generalized seizures, were evaluated in a ...
J Gordon Millichap, Millichap, J. Gordon
core   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

First case of topiramate-induced acute bilateral transient myopia in Saudi Arabia: case report and literature review

open access: yesBMC Neurology
Background Acute transient myopia with shallowing of the anterior chamber is a rare idiosyncratic response to many systemic and topical medications, including topiramate.
Rawan Albalawi   +2 more
doaj   +1 more source

Topiramate and accommodation: Does topiramate cause accommodative dysfunction?

open access: yes, 2017
Objective: To investigate the accommodation function in topiramate users. Design:Case-control clinical study. Participants:The participants included 16 controls and 22 patients using 100 mg/kg topiramate who were diagnosed with migraine according to the ...
ÇERMAN, EREN   +4 more
core   +1 more source

Hypohidrosis-related symptoms in pediatric epileptic patients with topiramate

open access: yes, 2010
Background: Topiramate is one of the most commonly prescribed newer antiepileptic drugs. However, we have encountered quite a few cases of pediatric epileptic patients on topiramate complaining about the symptoms related to hypohidrosis.
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core   +1 more source

When Tics and Autism Meet: Phenomenology, Severity, and Treatment Patterns

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Tic disorders frequently co‐occur with neurodevelopmental conditions, including autism spectrum disorder (ASD). However, the impact of ASD on tic phenomenology, severity, and treatment patterns remains incompletely understood. Objectives To compare clinical characteristics, tic phenomenology, severity, and treatment patterns in ...
Fatimah Aldurayhim   +3 more
wiley   +1 more source

Treatment of obese patients with binge eating disorder using topiramate: a review

open access: yesNeuropsychiatric Disease and Treatment, 2009
Paolo Leombruni, Luca Lavagnino, Secondo FassinoDepartment of Neurosciences, Psychiatry Section, University of Torino, Centre for Eating Disorders and Obesity, Torino, ItalyAbstract: Topiramate is an anticonvulsant drug used for the treatment of epilepsy
Paolo Leombruni   +2 more
doaj  

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

open access: yesPM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy   +3 more
wiley   +1 more source

Infantile Spasms Respond Poorly to Topiramate Monotherapy

open access: yes, 2014
Objective: To determine the rate of infantile spasms (IS) remission with topiramate monotherapy. Methods: We retrospectively analyzed the rate of clinical remission for all IS patients treated with topiramate monotherapy from January 2009 to March 2014 ...
Cole, Justin W.   +2 more
core  

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen   +6 more
wiley   +1 more source

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