Results 201 to 210 of about 830,462 (248)

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

open access: yesAdvanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang   +12 more
wiley   +1 more source

LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening

open access: yesAdvanced Science, EarlyView.
LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico   +7 more
wiley   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

open access: yesAdvanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty   +4 more
wiley   +1 more source

Molecular Rectification: Mechanisms, Modulation Strategies, and Device Realization

open access: yesAdvanced Science, EarlyView.
This review focuses on molecular rectification, from its fundamental mechanisms and modulation strategies to device realization. It summarizes the theoretical framework, modulation strategies, fabrication techniques, characterization methods, and modeling and simulation of molecular rectifiers, while discussing challenges and future directions for ...
Junnan Guo   +8 more
wiley   +1 more source

EEG microstate reconfiguration across cognitive states in preschool children with developmental language disorder. [PDF]

open access: yesFront Neurosci
Liang A   +9 more
europepmc   +1 more source

Chiral‐Nematic Lattice Instability in Charge Density Wave of 1T‐TiSe2

open access: yesAdvanced Science, EarlyView.
The charge density wave of 1T‐TiSe2 appears chiral to surface probes yet loses all symmetry in spectroscopic measurements. This study reveals how cooperative condensation of multiple phonon modes stabilizes a chiral monoclinic ground state, while a shallow nematic energy landscape allows the lattice to break the remaining symmetry at negligible cost ...
Abdurrafi Ahsan Alghifari   +3 more
wiley   +1 more source

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