Results 121 to 130 of about 129,599 (186)

Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

Advanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin, Zijie Chen, Yurong Li, Meijing Fang, Longji Shen, Yilong Su, Odin Zhang, Qinghan Wang, Qun Su, Jike Wang, Tingjun Hou, Yu Kang   +11 more
wiley   +1 more source

Strain engineering of topological transitions in 2D materials: a multi-band approach. [PDF]

Sci Rep
Azizi F.
europepmc   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

Advanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole, Andrew Lai, Alexander Quinn, Marianne Gillard, Dominic Guanzon, Katherin Scholz‐Romero, Alexis Salas‐Burgos, Bastián Lillo Dapremont, Rohan Lourie, Naven Chetty, Richard Lobb, Kate Beecher, Amy E. McCart Reed, Kaltin Ferguson, Biao Sun, Yaowu He, John D. Hooper, Carlos Salomon   +17 more
wiley   +1 more source

Generalized non-Hermitian Hamiltonian for guided resonances in photonic crystal slabs. [PDF]

Nanophotonics
Nguyen VA, Nguyen HS, Yuan Z, Nguyen DX, Dang C, Ha ST, Letartre X, Le-Van Q, Nguyen HS.   +8 more
europepmc   +1 more source

Constructing Seamless Interfaces for Ultrastable Flexible Supercapacitors

Advanced Science, EarlyView.
Seamless electrode/electrolyte and electrolyte/electrolyte interfaces with boosted interfacial toughness and adhesion are constructed by anchored interfacial polymerization and in situ polymerization, respectively. The achieved supercapacitor exhibits ultrahigh capacitance retention over 100,000 times of charge/discharge or folding deformation ...
Keyi Dong, Zefeng Yan, Weiyang Tang, Quanhu Sun, Jiaxin Yang, Yan Tan, Yu Wang, Tian Lv, Tao Chen   +8 more
wiley   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Discovery of an Ideal Quadratic Nodal Point in Two-Dimensional Binary Compound C₅P₁. [PDF]

ACS Omega
Li Y.
europepmc   +1 more source

Decoupling Intrinsic Molecular Efficacy From Platform Effects: An Interpretable Machine Learning Framework for Unbiased Perovskite Passivator Discovery

Advanced Science, EarlyView.
This study establishes an interpretable machine learning framework that disentangles the intrinsic molecular efficacy of passivators from experimental platform effects—enabling unbiased, high‐throughput discovery of effective perovskite surface modifiers.
Jing Zhang, Ziyuan Li, Shan Gao, Zhen Zhu, Jing Wang, Xiangmei Duan   +5 more
wiley   +1 more source

Electric-Current-Assisted Nucleation of Zero-Field Hopfion Rings. [PDF]

Adv Mater
Chen X, Song D, Rybakov FN, Kiselev NS, Li L, Shi W, Wu R, Fu X, Eriksson O, Blügel S, Dunin-Borkowski RE, Du H, Zheng F.   +12 more
europepmc   +1 more source

Helical Electron Beam Micro‐Bunching by High‐Order Modes in a Micro‐Plasma Waveguide

Advanced Science, EarlyView.
ABSTRACT Electron acceleration by a high‐power Laguerre‐Gaussian pulse in a micro‐plasma waveguide is investigated. When the incident laser travels in the waveguide, electrons on the wall are extracted into the vacuum core and accelerated by the longitudinal field of the waveguide mode.
Xingju Guo, Longqing Yi
wiley   +1 more source