Angewandte Chemie, EarlyView.Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee +5 more
wiley +2 more sources
Trainable Hydrogels: Mechanistic Principles, Training Strategies, and Frontier Applications. [PDF]
SmallLiu S +7 more
europepmc +1 more source
AI &Innovation, EarlyView.ABSTRACT Maintaining an effective balance between exploration and exploitation is essential during optimization processes, from mathematical functions to more complex problems such as constrained engineering design optimization, particularly when addressing highly nonlinear issues with numerous local optima and strict feasibility requirements.
Enrique Lizárraga +3 more
wiley +1 more source
q -Stirling sequence spaces associated with q -Bell numbers
Q -STIRLING SEQUENCE SPACES ASSOCIATED WITH Q -BELL NUMBERS Open mathematics (Rights reserved) (-) A kind of identities related to Riemann zeta-function / Chen, Zhuoyu (CC BY) (-) Multiple solutions for the p -biharmonic equation with a ...
Karakaş, Murat +3 more
core
Engineering Ferrimagnetic Interactions in Molecular Quantum Systems
Angewandte Chemie, EarlyView.Heterospin nanographene architectures—constructed by covalently linking spin‐1/2$\nicefrac {1}{2}$ and spin‐1 triangular units via on‐surface synthesis—are characterized by bond‐resolved scanning probe microscopy. Inelastic electron tunneling spectroscopy probes exchange interactions within a Heisenberg model, revealing both compensated (S=0$S=0$) and ...
Elia Turco +8 more
wiley +2 more sources
Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway
Animal Models and Experimental Medicine, EarlyView.This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu +5 more
wiley +1 more source
Multiple positive solutions to a p -Kirchhoff equation with logarithmic terms and concave terms
MULTIPLE POSITIVE SOLUTIONS TO A P -KIRCHHOFF EQUATION WITH LOGARITHMIC TERMS AND CONCAVE TERMS Open mathematics (Rights reserved) (-) A kind of identities related to Riemann zeta-function / Chen, Zhuoyu (CC BY) (-) Multiple solutions for ...
Liang, Jin-Ping +2 more
core
Decrypting potential mechanisms linking ochratoxin A to hepatocellular carcinoma: an integrated approach combining toxicology, machine learning, molecular docking, and molecular dynamics simulation. [PDF]
BMC Pharmacol ToxicolZhuo J +6 more
europepmc +1 more source
On the weak convergence of multiparameter stochastic integrals
ON THE WEAK CONVERGENCE OF MULTIPARAMETER STOCHASTIC INTEGRALS Open mathematics (Rights reserved) (-) A kind of identities related to Riemann zeta-function / Chen, Zhuoyu (CC BY) (-) Multiple solutions for the p -biharmonic equation with a ...
Boukfal, Salim, Bardina, Xavier
core
Topological Progress Potential-Enhanced Continuous-Space Ant Colony Algorithm for Robot Path Planning. [PDF]
Sensors (Basel)Dong G +5 more
europepmc +1 more source