Results 31 to 40 of about 2,865,251 (255)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Vertex-Edge-Degree-Based Topological Properties for Hex-Derived Networks

open access: yesComplexity, 2022
A topological index can be focused on uprising of a chemical structure into a real number. The degree-based topological indices have an active place among all topological indices.
Ali Ahmad, Muhammad Imran
doaj   +1 more source

Composite Topological Objects in Topological Superfluids

open access: yes, 2020
| openaire: EC/H2020/694248/EU//TOPVACThe spontaneous phase coherent precession of magnetization, discovered in 1984 by Borovik-Romanov, Bunkov, Dmitriev, and Mukharskiy [1] in collaboration with Fomin [2], became now an important experimental tool for ...
Volovik, G. E.
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Computation of Revan Topological Indices for Phenol-Formaldehyde Resin

open access: yesJournal of Mathematics, 2022
Phenol-formaldehyde resin has a wide range of moldings. The phenolic resin retains properties at the freezing point; hence, it is difficult to determine its age.
Muhammad Kamran   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Periodic and bounded solutions of functional differential equations with small delays

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2022
We study existence and local uniqueness of periodic solutions of nonlinear functional differential equations of first order with small delays. Bifurcations of periodic and bounded solutions of particular periodically forced second-order equations with ...
Michal Fečkan, Július Pačuta
doaj   +1 more source

Topological Complexity of Configuration Spaces [PDF]

open access: yes, 2010
In this thesis we study the homotopy invariant TC(X); the topological complexity of a space X. This invariant, introduced by Farber in [15], was originally motivated by a problem in Robotics; the motion planning problem.
COSTA, ARMINDO,EMANUEL   +1 more
core  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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