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From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

A novel approach integrating topological deep learning from EEG Data in Alzheimer's disease. [PDF]

open access: yesSci Rep
Esteve M   +4 more
europepmc   +1 more source
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Topological Dynamic Matter

The Journal of Physical Chemistry Letters, 2020
The principles of topology in condensed matter physics have expanded to areas such as photonics, acoustics, electronics, and mechanics. Their extension to dynamic (soft) matter could enable the control and design of topological thermodynamic (micro)states and nonreciprocal dynamics, potentially leading to paradigmatic applications in molecular and ...
openaire   +2 more sources

Dynamic topology representing networks

Neural Networks, 2000
In the present paper, we propose a new algorithm, namely the Dynamic Topology Representing Networks (DTRN) for learning both topology and clustering information from input data. In contrast to other models with adaptive architecture of this kind, the DTRN algorithm adaptively grows the number of output nodes by applying a vigilance test. The clustering
J, Si, S, Lin, M A, Vuong
openaire   +2 more sources

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