FusionEP: Adaptive Cross-Modal Deep Fusion Network for Essential Protein Identification via Multi-Omics Integration and Contrastive Learning. [PDF]
Entropy (Basel)Wu C +5 more
europepmc +1 more source
Axiomatic definition of the topological entropy on the interval
Summary. The aim of this paper is to give an axiomatic definition of the topological entropy for continuous interval maps and, in such a way, to shed some more light on the importance of the different properties of the topological entropy in this setting.
Llibre Saló, Jaume +3 more
core
Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis
Advanced Science, EarlyView.Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko +8 more
wiley +1 more source
Entropic Confinement in String-Net Models: An Analogue Study via SU(2)<sub>k</sub> Fusion Categories. [PDF]
Entropy (Basel)Yang X.
europepmc +1 more source
Topological entanglement entropy relations for multi phase systems with interfaces
, 2010 We study the change in topological entanglement entropy that occurs when a two-dimensional system in a topologically ordered phase undergoes a transition to another such phase due to the formation of a Bose condensate.
Slingerland, Joost, Bais, F.A.
core
The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells
Advanced Science, EarlyView.Purely geometric 3D Voronoi models predict the organisation of epithelial shells. The interplay of curvature, geometry, and topology enriches the number of pentagons in shells with lower number of cells. Small MDCK cysts and Mouse embryos match the top polygonal configurations in a compactness‐based ranking derived from the Voronoi model. In conclusion,
Laura Morato +9 more
wiley +1 more source
Topological Organization of Center-of-Pressure Dynamics During Virtual Reality Walking Differs Between Individuals With Parkinson's Disease and Healthy Older Adults. [PDF]
Health Sci RepAzadian E +4 more
europepmc +1 more source
Advanced Science, EarlyView.Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu +8 more
wiley +1 more source
Lempel-Ziv Complexity and Structural Features of DNA Methylation Reveal Epigenetic Rejuvenation in Mouse Embryogenesis. [PDF]
Genes (Basel)Timofeev AV, Bratchikov A, Anufriev A.
europepmc +1 more source
A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation
Advanced Science, EarlyView.A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang +5 more
wiley +1 more source