Results 41 to 50 of about 17,983 (296)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Topological entropy of DNA sequences [PDF]

open access: yesBioinformatics, 2011
Abstract Motivation: Topological entropy has been one of the most difficult to implement of all the entropy-theoretic notions. This is primarily due to finite sample effects and high-dimensionality problems. In particular, topological entropy has been implemented in previous literature to conclude that entropy of exons is higher than of ...
openaire   +3 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Influence Maximization Dynamics and Topological Order on Erdös-Rényi Networks

open access: yesMathematics, 2023
This paper concerns the study of the linear threshold model in random networks, specifically in Erdös-Rényi networks. In our approach, we consider an activation threshold defined by the expected value for the node degree and the associated influence ...
J. Leonel Rocha   +4 more
doaj   +1 more source

A Comment on the Relation between Diffraction and Entropy

open access: yes, 2012
Baake M, Grimm U. A Comment on the Relation between Diffraction and Entropy. Entropy. 2012;14(12):856-864.Diffraction methods are used to detect atomic order in solids.
Uwe Grimm   +3 more
core   +1 more source

On two notions of fuzzy topological entropy

open access: yes, 2022
We explore the notion of fuzzy topological entropy when different definitions of fuzzy compactness are considered. We prove that the recent de finitions by Tok and by Uzzal Afsan and Basu are not the most appropriate since they always display zero ...
Kupka, Jiri   +1 more
core   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

Non-extensive entropy and holographic thermodynamics: topological insights

open access: yesEuropean Physical Journal C: Particles and Fields
In this paper, we delve into the thermodynamic topology of AdS Einstein–Gauss–Bonnet black holes, employing non-extensive entropy formulations such as Barrow, Rényi, and Sharma–Mittal entropy within two distinct frameworks: bulk boundary and restricted ...
Saeed Noori Gashti, Behnam Pourhassan
doaj   +1 more source

A remark on positive topological entropy of N-buffer switched flow networks

open access: yesDiscrete Dynamics in Nature and Society, 2005
We present a simpler elementary proof on positive topological entropy of the N-buffer switched flow networks based on a new simple theorem on positive topological entropy of continuous map on compact metric space.
Xiao-Song Yang
doaj   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

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