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Aspects of Topological String Theory [PDF]

open access: yes, 2008
Two aspects of the topological string and its applications are considered in this thesis. Firstly, non-perturbative contributions to the OSV conjecture relating four-dimensional extremal black holes and the closed topological string partition function ...
Cook, Paul Langabi Hogan
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Topological transitions in weakly monitored free fermions

open access: yesSciPost Physics, 2023
We study a free fermion model where two sets of non-commuting non-projective measurements stabilize area-law entanglement scaling phases of distinct topological order.
Graham Kells, Dganit Meidan, Alessandro Romito
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Non-extensive entropy and holographic thermodynamics: topological insights

open access: yesEuropean Physical Journal C: Particles and Fields
In this paper, we delve into the thermodynamic topology of AdS Einstein–Gauss–Bonnet black holes, employing non-extensive entropy formulations such as Barrow, Rényi, and Sharma–Mittal entropy within two distinct frameworks: bulk boundary and restricted ...
Saeed Noori Gashti, Behnam Pourhassan
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Tree shift topological entropy [PDF]

open access: yesTheoretical Computer Science, 2018
Final version (with changed title), to appear in Theoretical Computer ...
Karl Petersen, Ibrahim Salama
openaire   +4 more sources

Entropy - A Guide for the Perplexed [PDF]

open access: yes, 2010
Entropy is ubiquitous in physics, and it plays important roles in numerous other disciplines ranging from logic and statistics to biology and economics.
Werndl, Charlotte   +3 more
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

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