Results 191 to 200 of about 993 (249)

The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley   +1 more source

Dynamic Holographic Display With Multiplexed Dielectric Metasurfaces

open access: yesNanophotonics, Volume 15, Issue 12, 25 June 2026.
Based on multiplexed metasurfaces, we show hybrid multiplexing of polarization, wavelength, and orbital angular momentum can be applied for dynamic tuning. Our strategy presents a highly compact and efficient solution for high‐capacity, multi‐dimensional holography, with promising applications in advanced displays, data storage, optical encryption, and
Yu Liu   +8 more
wiley   +1 more source

Magnetically Reconfigurable Mode Strong Coupling Toward Tunable Nanophotonic Sensing Devices

open access: yesNanophotonics, Volume 15, Issue 12, 25 June 2026.
A magnetically reconfigurable metasurface realizes tunable strong coupling between structural and magneto‐structurally induced q‐BIC resonances without changing device geometry. The resulting hybrid branches enable high‐sensitivity refractive‐index sensing with noncontact active control, large figure of merit, and multiple resonance observables ...
Runmin Liu   +5 more
wiley   +1 more source

Oxoaporphine‐Metformin Rhodium(III) Hybrid Ionic Complex With Antidiabetes and Anticancer Effects: New Insights From DFT Computations

open access: yesInternational Journal of Quantum Chemistry, Volume 126, Issue 12, June 15, 2026.
DFT (GGA) analysis reveals that the Rh‐Met metallodrug forms a stable ionic pair driven by a network of supramolecular interactions. QTAIM and IGMH insights elucidate the quantum‐mechanical nature of intra‐ and intermolecular contacts governing its self‐assembly and structural organization in the crystal. ABSTRACT A recently proposed (J. Am. Chem. Soc.
Costantino Zazza   +2 more
wiley   +1 more source

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