Results 51 to 60 of about 9,365,022 (258)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 1984 Let H be a topological group and a subgroup of G. A topology on G is called an extending topology if and only if it makes G a topological group and it induces the given topology on H. The set of all such topologies is studied.
Bradd Clark, Victor Schneider
doaj +1 more source
Pro-Lie Groups: A Survey with Open Problems
Axioms, 2015 A topological group is called a pro-Lie group if it is isomorphic to a closed subgroup of a product of finite-dimensional real Lie groups. This class of groups is closed under the formation of arbitrary products and closed subgroups and forms a complete ...
Karl H. Hofmann, Sidney A. Morris
doaj +1 more source
Countable networks on Malykhin's maximal topological group
Applied General Topology, 2023 We present a solution to the following problem: Does every countable and non-discrete topological (Abelian) group have a countable network with infinite elements?
Edgar Márquez
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Some Analogues of Topological Groups
Discussiones Mathematicae - General Algebra and Applications, 2021 Let (G, ∗) be a group and τ be a topology on G. Let τα = {A ⊆G : A ⊆ Int(Cl(Int(A)))}, g ∗ τ = {g ∗ A : A ∈ τ} for g ∈ G. In this paper, we establish two relations between G and τ under which it follows that g ∗ τ ⊆ τα and g ∗ τα ⊆ τα, designate them by ...
Ram Madhu
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Antea Group Archeologie 2019/164
, 2020 projectnummer 456639 rapportvolgnummer 2019/164 De aanleiding tot het uitvoeren van dit bureauonderzoek en inventariserend veldonderzoek door middel van boringen is de voorgenomen sanering c.q.
Fens, R. (Antea Group) +9 more
core +1 more source
Antea Group Archeologie 2020/159
, 2021 In augustus 2020 – maart 2021 heeft Antea Group een archeologisch bureauonderzoek en inventariserend veldonderzoek uitgevoerd ter voorbereiding op het verleggen van een DN400 drinkwaterleiding in Ewijk, gemeente Beuningen.
Fens, R.L. (Antea Group) +1 more
core +1 more source