Results 231 to 240 of about 835,518 (294)

Impact of Threading State on the Mechanics of γ‐Cyclodextrin–Pyrene Gels

open access: yesAngewandte Chemie, EarlyView.
Tuning the threading state of discrete γ‐cyclodextrin (γ‐CD)–pyrene pseudorotaxane crosslinkers controls gel topology and ring mobility. The resulting doubly threaded slide‐ring networks exhibit solvent‐switchable dissipative dynamics, high extensibility, rate‐dependent mechanics, and low hysteresis, revealing how crosslink topology governs macroscopic
Jongwon Oh   +8 more
wiley   +2 more sources

Genome‐wide network analysis identifies the lncRNA‐92467/miR‐205‐5p/PTPRM/CAMs axis in a rat model of hypoxic pulmonary hypertension

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen   +7 more
wiley   +1 more source

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu   +4 more
wiley   +1 more source

Role of Graphene Oxide in the Nucleation and Growth of Gold Nanoparticles Revealed by Operando Time‐Resolved Studies

open access: yesAngewandte Chemie, EarlyView.
Graphene oxide accelerates AuCl4− reduction under irradiation and directs edge‐selective nucleation and quasi‐one‐dimensional organization of gold nanoparticles at oxygen‐rich boundaries. Operando SAXS and UV–vis spectroscopy, supported by pulse radiolysis and DFT, reveal how progressive conversion of GO to rGO removes interfacial constraints, shifting
Liran Hu   +9 more
wiley   +1 more source

Bottlebrush Polyolefin Sulfones as Triggerable and Degradable Pressure‐Sensitive Adhesives

open access: yesAngewandte Chemie, EarlyView.
A grafting‐through alternating copolymerization strategy yields poly(norbornene sulfone) bottlebrush polymers with high molar mass. These materials function as additive‐free pressure‐sensitive adhesives. The incorporation of cleavable sulfone units enables rapid breakdown under mild alkaline conditions, providing a pathway toward sustainable, high ...
Clark Vu   +5 more
wiley   +1 more source

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