Results 201 to 210 of about 4,855,956 (246)

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

Enthalpy-Driven Topological Programming of (TPMS)-Like Carbon Networks. [PDF]

Adv Mater
Ma J, Liu Z, Zhu P, Ma M, Wang B, Cui P, Zhang B, Qin L, Kang Y, Ji Z, Tian K, Wu F, Fei G, Che R, Huang W.   +14 more
europepmc   +1 more source

Designer Moiré Quantum Materials Enabled by Freestanding Oxide Membranes in Twisted and Hybrid Bilayers

Advanced Science, EarlyView.
Freestanding oxide membranes transform twistronics by enabling deterministic stacking, strain release, and integration with two‐dimensional materials. A unified framework links local atomic registry to structural reconstruction, polar textures, charge modulation, flat bands, and magnetic responses, while identifying the fabrication and characterization
Puneet Kaur, Rahul, Jan‐Chi Yang
wiley   +1 more source

Chirobiophore: A Novel Framework for Quantifying Biochirality in Macromolecular Systems. [PDF]

Biomolecules
Lungu CN, Basak SC.
europepmc   +1 more source

Cross‐scale Material‐Structure Synergy for 2D Metamaterials: Toward Customizable Intelligent Electromagnetic Manipulation in Multiphysics Fields

Advanced Science, EarlyView.
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang, Xing Yang, Liping Liu, Yang Peng, Yangyang Wang, Hualiang Lv   +5 more
wiley   +1 more source

Plasmonic Dirac-vortex lasers via three-dimensional photonic mass vortices engineering. [PDF]

Nat Commun
Zhong M, Bi X, Song M, Mou N, Zhang D, Zhuo X, Hu J, Xie B, Ao X, Guan J.   +9 more
europepmc   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

HMA-GCA: hybrid manifold augmentation and gated cross-attention for circRNA-miRNA interaction prediction. [PDF]

Bioinformatics
Hu Y, Wang Y, Bai Y, Xu L, Zou Q, Zhou H, Wang C, Niu M.   +7 more
europepmc   +1 more source

Temperature‐Modulated MEMS Gas Sensor Array Enabled by Physics‐Informed Deep Learning for Thermal‐Runaway Characteristic Gas Discrimination

Advanced Science, EarlyView.
This work presents a 2 × 2 integrated single‐chip MEMS gas sensor array with temperature modulation and deep learning for discriminating thermal‐runaway characteristic gases. The array generates distinct temperature‐modulated response patterns for four characteristic gases (H2, CO, CH4, and CO2), while a HK‐MoE model is developed to achieve robust ...
Qin Luo, Qi Guo, Rongyue Liu, Yilin Li, Haiping Zhu, Wei Zhang, Zhongren Chen, Zhaojun Liu, Xing Cheng   +8 more
wiley   +1 more source

Chip-integrated metasurface-enabled single-photon skyrmion sources. [PDF]

Nat Commun
Liu X, Kan Y, Kumar S, Kulikova LF, Davydov VA, Agafonov VN, Bozhevolnyi SI.   +6 more
europepmc   +1 more source