Results 271 to 280 of about 1,877,349 (376)

Geometry‐Guided Osteogenesis in Bone‐on‐a‐Chip Systems Using Triply Periodic Minimal Surface Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim   +5 more
wiley   +1 more source

An Ultra‐Flexible Neural Electrode with Bioelectromechanical Compatibility and Brain Micromotion Detection

open access: yesAdvanced Healthcare Materials, EarlyView.
Neural electrodes face a mechanical mismatch with brain tissue. This study proposes a bioelectromechanical coupling strategy using an ultra‐flexible electrode designed for synchronized motion. Optimized to match brain tissue stiffness, it achieves dual signal acquisition and micromotion sensing, with characterized interfacial forces and piezoresistive ...
Donglei Chen   +11 more
wiley   +1 more source

Erratum to: How can functional annotations be derived from profiles of phenotypic annotations?

open access: yesBMC Bioinformatics, 2017
Beatriz Serrano-Solano   +3 more
doaj   +1 more source

AI‐Assisted Design and Evaluation of SLM‐Ti64 Implants for Enhanced Bone Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
AI‐driven simulations of biological healing, combining biomechanical modeling and machine learning, enable personalized orthopedic treatments. By decoding healing patterns influenced by implants and patient‐specific factors, this approach advances fracture repair understanding, optimizes implant design, and supports precision medicine and sustainable ...
Muhammad Usama Zaheer   +3 more
wiley   +1 more source

Disrupting Amyloid Filaments of Tau by Means of Electric Fields. [PDF]

open access: yesJ Phys Chem B
Vargas-Rosales PA   +2 more
europepmc   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

open access: yesAdvanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour   +11 more
wiley   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

open access: yesAdvanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao   +4 more
wiley   +1 more source

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