Results 161 to 170 of about 79,997 (252)

A Conserved Macrophage-to-Hepatic Stellate Cell PDGF Axis in Human MASH Identified by Multi-Cohort sc/snRNA-Seq Re-Analysis. [PDF]

Int J Mol Sci
Ling H, Qiu P, Hu Y.
europepmc   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Hyperbolic adaptive spatial-aware multivariate time series anomaly detection. [PDF]

Nat Commun
Han J, Huo X, Xiao Y, Ye Z, Zheng Y, Zhao H, Sun M, Liu Z.   +7 more
europepmc   +1 more source

Physics‐Aware Machine‐Learning‐Driven Inverse Design of Broadband Ultra‐Open Acoustic Metamaterials

Advanced Science, EarlyView.
A physics‐aware machine‐learning framework enables inverse design of ultra‐open acoustic silencers by decoupling spectral and radial design spaces. The approach rapidly identifies broadband, compact, and highly ventilated architectures, while revealing hidden linear design rules that link geometry, impedance matching, and acoustic performance.
Zhiwei Yang, Mengyu Li, Xiaohang Xie, Ao Chen, Thomas G. Bifano, Xin Zhang   +5 more
wiley   +1 more source

Artificial Intelligence for Therapeutic Peptide Discovery and Development. [PDF]

Biomolecules
Ventura S.
europepmc   +1 more source

Development of proteome-derived cyclic peptide libraries via ortho-phthalaldehyde-assisted cyclization. [PDF]

iScience
Wei Y, Feng K, Hou W, Tian X, Xue Y, Zhang W, Deng H.   +6 more
europepmc   +1 more source

Anchor Engineering of Hole‐Selective Enamine‐Based Self‐Assembling Monolayers for Perovskite Solar Cells

Advanced Science, EarlyView.
This work presents novel enamine‐based self‐assembling monolayers with engineered anchoring groups as hole‐selective contacts for inverted perovskite solar cells. The conjugated molecular design suppresses interfacial defects, optimizes charge extraction, and prevents aggregation.
Deimante Krisiune, Yuxuan Yang, Yongde Xu, Hao Tian, Chuanxiao Xiao, Jianxing Xia, Mahan Saberi Zafarghandi, Ali Keshavarz Mohammadian, Negar Ashari Astani, Kasparas Rakstys, Yi Zhang, Vytautas Getautis   +11 more
wiley   +1 more source

Complete Linker Desymmetrization Enabled Construction of an eft-Topological Zr(IV)-MOF Comprising Two Types of Hexazirconium Nodes for Ammonia Capture. [PDF]

Angew Chem Int Ed Engl
Gao P, Zhang J, Geng Y, Jiang C, Cui Y, Gong W.   +5 more
europepmc   +1 more source