Results 141 to 150 of about 4,783,589 (360)

An efficient 3D homogenization-based topology optimization methodology [PDF]

, 2021
Konstantinos-Iason Ypsilantis, George Kazakis, Nikos D. Lagaros   +2 more
openalex   +1 more source

An Ultra‐Flexible Neural Electrode with Bioelectromechanical Compatibility and Brain Micromotion Detection

Advanced Healthcare Materials, EarlyView.
Neural electrodes face a mechanical mismatch with brain tissue. This study proposes a bioelectromechanical coupling strategy using an ultra‐flexible electrode designed for synchronized motion. Optimized to match brain tissue stiffness, it achieves dual signal acquisition and micromotion sensing, with characterized interfacial forces and piezoresistive ...
Donglei Chen, Yu Lu, Shuo Zhang, Wenqi Zhang, Zejie Yu, Shuideng Wang, Zhi Qu, Mingxing Cheng, Yiqing Yao, Deheng Wang, Zhan Yang, Lixin Dong   +11 more
wiley   +1 more source

PARAMETRIC LEVEL SET METHOD-BASED TOPOLOGY OPTIMIZATION OF HEAT CONDUCTION STRUCTURES

Jixie qiangdu, 2018
With the problems of complicated calculation process and lower computational efficiency in topology optimization using the traditional level set method（LSM） of heat conduction structures,parametric level set method（PLSM） is introduced into topology ...
SHEN YaDong, FENG JianHu, CHENG XiaoHan
doaj  

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Topology Optimization Design of Transfer Case Housing

Jixie chuandong, 2016
The topology optimization design of the complicated transfer case housing is conducted by using the variable density method. Taking the minimum compliance as the optimization objective and the volume fraction,static displacement,static stress,modal ...
Zhang Qing, Zhang Bin, Li Hongbiao, Huo Chunjing, Yang Xianxue   +4 more
doaj  

Topology Analysis and Structural Optimization of Air Suspension Mechanical-Vibration-Reduction Wheels [PDF]

Meng Xiao, Xianying Feng, P.J. Liu, Xinhua Sun   +3 more
openalex   +1 more source

A 99 line topology optimization code written in Matlab

, 2001
O. Sigmund
semanticscholar   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

Kinematic Analysis of Prosthetic Knee Joint and Topology Optimization of Front Linkage Rod [PDF]

Zhifeng Nie, Kai Wang
openalex   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source