Results 41 to 50 of about 700 (252)

Category-Theoretical and Topos-Theoretical Frameworks in Machine Learning: A Survey

Axioms
In this survey, we provide an overview of category theory-derived machine learning from four mainstream perspectives: gradient-based learning, probability-based learning, invariance and equivalence-based learning, and topos-based learning.
Yiyang Jia, Guohong Peng, Zheng Yang, Tianhao Chen   +3 more
doaj   +1 more source

Models of Type Theory Based on Moore Paths [PDF]

Logical Methods in Computer Science, 2019
This paper introduces a new family of models of intensional Martin-L\"of type theory. We use constructive ordered algebra in toposes. Identity types in the models are given by a notion of Moore path.
Ian Orton, Andrew M. Pitts
doaj   +1 more source

Negations and Meets in Topos Quantum Theory [PDF]

Foundations of Physics, 2021
The daseinisation is a mapping from an orthomodular lattice in ordinary quantum theory into a Heyting algebra in topos quantum theory. While distributivity does not always hold in orthomodular lattices, it does in Heyting algebras. We investigate the conditions under which negations and meets are preserved by daseinisation, and the condition that any ...
openaire   +2 more sources

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Topos Theory and ‘Neo-Realist’ Quantum Theory [PDF]

, 2009
Topos theory, a branch of category theory, has been proposed as mathematical basis for the formulation of physical theories. In this article, we give a brief introduction to this approach, emphasising the logical aspects. Each topos serves as a `mathematical universe' with an internal logic, which is used to assign truth-values to all propositions ...
openaire   +2 more sources

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Taming the Immiscibility of Gold, Iron, and Boron to Craft Chemodegradable Nanoparticles for Multimodal Imaging and Radiotherapy

Advanced Healthcare Materials, EarlyView.
Over half of cancer patients undergo radiotherapy. Laser ablation enabled the synthesis of immiscible Au‐Fe‐B nanoparticles designed as degradable bimodal radiosensitizers for X‐ray radiotherapy (XRT), boron neutron capture therapy (BNCT), and bimodal imaging for X‐ray computed tomography (CT) and magnetic resonance imaging (MRI). These nanosensitizers
Michael Bissoli, Clara M.G. de Faria, Veronica Torresan, Maria Assunta Lacavalla, Mattia Cattelan, Denis Badocco, Paolo Pastore, Pasquina Marzola, Laura Cansolino, Cinzia Ferrari, Ian Postuma, Riccardo Vago, Silva Bortolussi, Antonello E. Spinelli, Daniel Forrer, Vincenzo Amendola   +15 more
wiley   +1 more source

Pour une théorie périphérique et/ou amoureuse : lectures d’Agamben, Derrida, Rancière

Interlitteraria, 2020
For a Peripheral Theory in Love: Reading Agamben, Derrida, Rancière. The introduction of Giorgio Agamben’s book entitled Stanzas, Word and Phantasm in Western Culture is about the relationship of philosophy and poetry to knowledge in Western culture. The
Francesca Manzari
doaj   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source