Results 61 to 70 of about 687,146 (243)
The target of rapamycin (TOR) complex is a central plant growth regulator. Here, the protein–protein interactions underlying its various functions are mapped by pupylation‐based proximity‐labeling in Arabidopsis, using TOR complex subunits LST8‐1 and RAPTOR1, alongside TOR inhibitor FK506‐binding protein, as baits.
Shuai Zheng+9 more
wiley +1 more source
Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra+3 more
wiley +1 more source
EccDNA‐Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation
Following ionizing radiation, eccDNA‐mediated VPS41 amplification slightly increases its expression but fails to prevent apoptosis. Introducing exogenous eccDNA or VPS41 enhances VPS41‐KAI1 interaction, promoting lysosomal degradation of KAI1. This process inhibits apoptotic signaling, enhancing cell survival and resistance to radiation‐induced damage.
Bin Shi+12 more
wiley +1 more source
Cohomological Descent for Faltings Ringed Topos
Faltings ringed topos, the keystone of Faltings’ approach to p-adic Hodge theory for a smooth variety over a local field, relies on the choice of an integral model, and its good properties depend on the (logarithmic) smoothness of this model. Inspired by
Tongmu He
doaj +1 more source
Dynamic Defect Tolerance in Metal Halide Perovskites: From Phenomena to Mechanism
Defect tolerance is the key feature that dominates the high performance of perovskite devices. MHPs exhibit dynamic defect tolerance at practical working condition, which is intrinsically relevant to their soft‐lattice thus mixed ionic‐electronic conduction, and intimately correlated with charge carrier, phonon, lattice, and mobile ions and determine ...
Guangsheng Liu+5 more
wiley +1 more source
A Hoehnke Radical on the Topos Act-s
One of the important concepts in topos theory is the concept of (weak) Lawvere-Tierney topology. A class of (weak) Lawvere topology on the topos Act-S of right acts over a fixed monoid S is ideal topology which has been introduced by the authors in ...
Ali Madanshekaf+1 more
doaj
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska+2 more
wiley +1 more source
Bootstrapping Inductive and Coinductive Types in HasCASL [PDF]
We discuss the treatment of initial datatypes and final process types in the wide-spectrum language HasCASL. In particular, we present specifications that illustrate how datatypes and process types arise as bootstrapped concepts using HasCASL's type ...
Lutz Schröder
doaj +1 more source
Ba<sub>2</sub>BP<sub>7</sub>N<sub>14</sub> - A Quaternary Alkaline Earth Nitridoborophosphate with a Mixed 3D Network Structure. [PDF]
The alkaline earth nitridoborophosphate Ba2BP7N14 was synthesized under high‐pressure high‐temperature conditions. The crystal structure reveals a 3D‐network of PN4 and mixed occupied (P0.75B0.25)N4 tetrahedra and was determined using a multi‐step characterization process including SCXRD, PXRD, elemental analysis, electron microscopy and NMR ...
Buda AT+4 more
europepmc +2 more sources