Results 81 to 90 of about 700 (252)
New biosensors and transgenic mice for multiplex cGMP imaging
British Journal of Pharmacology, EarlyView.Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters +6 more
wiley +1 more source
Argumentationsanalyse. Grundtræk af en modulær sprogvidenskabelig tilgang
Hermes, 1998 In this article, the author presents some fundamentals of a modular linguistic approach to argumentation. Argumentation is seen as a matter of interpretation, and since interpretation phenomena depend on linguistic material as well as on context in the ...
Henning Nølke
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Approach to formalization of the intelligent information control systems based on the topos theory
, 2021 D Avsykevich +2 more
openalex +1 more source
Humanities, 2012 The story of the Tower of Babel in Gn 11:1–9 gave rise to a rich literary tradition, in which the topos of the primeval language emerged. Whereas the interpretative tradition originating among the Jewish commentators upheld that the original language was
Juan Pedro Monferrer-Sala
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Topos quantum theory on quantization-induced sheaves [PDF]
Journal of Mathematical Physics, 2014 In this paper, we construct a sheaf-based topos quantum theory. It is well known that a topos quantum theory can be constructed on the topos of presheaves on the category of commutative von Neumann algebras of bounded operators on a Hilbert space. Also, it is already known that quantization naturally induces a Lawvere-Tierney topology on the presheaf ...
openaire +3 more sources
The FEBS Journal, EarlyView.midkine‐a (mdka), a pan‐injury response gene in vertebrates, is precisely regulated in the zebrafish telencephalon by a modular cis‐regulatory architecture. This control ensures proper expression during development, adult brain homeostasis, and regeneration.
Jincan Chen +6 more
wiley +1 more source
“Utinam ne in nemore Pelio”. Un verso di Ennio nelle opere di Cicerone [PDF]
Parole Rubate, 2019 Rapidly become a literary topos, Ennius’s line utinam ne in nemore Pelio refers to certain events one wished had not unfolded, given the far-reaching consequences they had. In his works, Cicero quotes Ennius’s line repeatedly.
Alessandra Di Meglio
doaj
Die diskoers tussen Job en Cloete struktureelsemanties beskou
Literator, 2002 A structural-semantic view of the discourse between Job and Cloete This article examines an aspect of the interaction between linguistics and literature. It is argued that the structural-semantic theory as developed by A.J.
J. Buscop
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Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
The FEBS Journal, EarlyView.PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
The FEBS Journal, EarlyView.Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source