Results 81 to 90 of about 673 (251)
Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
The FEBS Journal, EarlyView.PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
The FEBS Journal, EarlyView.Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source
History and Theory, EarlyView.ABSTRACT The problem of historical realism has gained some new momentum recently, with a fresh challenge to what is taken to be an anti‐realist hegemony in the theory and philosophy of history. Unfortunately, this has also provided the opportunity for the reheating of old polemics and lazy scholarship that characterized the 1990s reaction to ...
João Ohara
wiley +1 more source
Teoria kategorii i niektóre jej logiczne aspekty
Zagadnienia Filozoficzne w Nauce, 2018 This article is intended for philosophers and logicians as a short partial introduction to category theory (CT) and its peculiar connection with logic. First, we consider CT itself.
Mariusz Stopa
doaj
Argumentationsanalyse. Grundtræk af en modulær sprogvidenskabelig tilgang
Hermes, 1998 In this article, the author presents some fundamentals of a modular linguistic approach to argumentation. Argumentation is seen as a matter of interpretation, and since interpretation phenomena depend on linguistic material as well as on context in the ...
Henning Nølke
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Journal of Law and Society, EarlyView.Abstract Devolution since 1998 has seen administrations in England, Northern Ireland, Scotland, and Wales gain distinct powers over a range of policy fields, with health prominent among them. This poses two pressing questions for socio‐legal scholarship that we address in this article: to what extent are changing territorial arrangements significant ...
MATTHEW WATKINS +3 more
wiley +1 more source
Humanities, 2012 The story of the Tower of Babel in Gn 11:1–9 gave rise to a rich literary tradition, in which the topos of the primeval language emerged. Whereas the interpretative tradition originating among the Jewish commentators upheld that the original language was
Juan Pedro Monferrer-Sala
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Approach to formalization of the intelligent information control systems based on the topos theory
, 2021 D Avsykevich +2 more
openalex +1 more source
Artificial Creativity and Human Fragility
Modern Theology, EarlyView.Abstract This article critiques the widespread assumption that generative AI systems exhibit genuine artistic creativity. While such systems can produce novel and aesthetically appealing outputs, assessments based solely on results obscure fundamental differences between human and artificial agents.
Johanna Merz
wiley +1 more source
“Utinam ne in nemore Pelio”. Un verso di Ennio nelle opere di Cicerone [PDF]
Parole Rubate, 2019 Rapidly become a literary topos, Ennius’s line utinam ne in nemore Pelio refers to certain events one wished had not unfolded, given the far-reaching consequences they had. In his works, Cicero quotes Ennius’s line repeatedly.
Alessandra Di Meglio
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