Results 31 to 40 of about 49,217 (304)

Falling in Love with Scripture: Intellectuality and Emotionality in Lithuanian Haredi Torah Study

open access: yesReligions
This article examines the emotional and intellectual dimensions of Torah study in contemporary Lithuanian Haredi Judaism in Israel by analyzing the cultural construction of ahavat ha-Torah (love of Torah).
Yair Berlin
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Logic in the Torah [PDF]

open access: yes, 2018
Logic in the Torah is a ‘thematic compilation’ by Avi Sion. It collects in one volume essays that he has written on this subject in Judaic Logic (1995) and A Fortiori Logic (2013), in which traces of logic in the Torah and related religious documents ...
Sion, Avi
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Borderless Boundaries – as Means of Death and Life: Wilderness Portraits in Patristic and Rabbinic Literature [PDF]

open access: yes, 2015
This study examines the role played by environmental representation of an apparent borderless boundary, the desert, as presented in Scripture – the Hebrew Bible / First Testament.
Maoz, Daniel
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A atualidade do “hoje” em Dt 26,16-19

open access: yesPistis & Praxis: Teologia e Pastoral, 2019
Dt 26,16-19 possui um vocabulário específico e determinante, próprio do livro de Deuteronômio. Por isso, pode-se admitir, em particular, a sua capacidade de síntese do conjunto de leis contido em Dt 12–26*.
Leonardo Agostine Fernandes
doaj   +1 more source

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