The utility of urine biomarkers in diuretic resistance prediction in heart failure hospitalization. [PDF]
High urine pi‐GST concentration might be a marker for the development of loop diuretic resistance in patients with congestive heart failure hospitalization. Abstract Aims Loop diuretic resistance (LDR) in patients with heart failure hospitalization (HHF) is associated with worse clinical outcomes.
Imiela T +7 more
europepmc +2 more sources
In this study, electron beam irradiation technology was used to degrade torasemide in an aqueous solution. By investigating the degradation effect, its influencing factors, and degradation products, the radiation degradation characteristics and possible ...
ZHANG Zhibo +5 more
doaj +1 more source
High doses of torasemide in the doctor’s practice: obvious benefits
Today, torasemide is the most prescribed loop diuretic in clinical practice. Its high doses are used mainly in two clinical situations accompanied by hyperhydration: chronic heart failure (CHD) and chronic kidney disease (CKD).
D.D. Ivanov
doaj +1 more source
The diuretic torasemide does not prevent aldosterone-mediated mineralocorticoid receptor activation in cardiomyocytes. [PDF]
Aldosterone binds to the mineralocorticoid receptor (MR) and exerts pleiotropic effects beyond enhancing renal sodium reabsorption. Excessive mineralocorticoid signaling is deleterious during the evolution of cardiac failure, as evidenced by the benefits
Basile Gravez +6 more
doaj +1 more source
Preoperative Prediction Models for 30-Day All-Cause Mortality After Mitral Valve Repair in Dogs: A Single-Center Retrospective Cohort Study. [PDF]
ABSTRACT Background Mitral valve repair (MVR) has emerged as a novel surgical intervention for dogs with myxomatous mitral valve disease (MMVD). However, no objective risk assessment method has been established for these cases. Objectives The primary aim of this study was to develop and evaluate preoperative prediction models for 30‐day postoperative ...
Furusato S +5 more
europepmc +2 more sources
Pharmacogenetics as a Way for Personalizing Diuretic Therapy: Focus on Torasemide
Optimizing diuretic therapy in patients with chronic heart failure is a complicated problem with many unresolved questions. Diuretics take an important place in the treatment of heart failure, which are used in almost 80% of cases.
N. M. Gafurova +2 more
doaj +1 more source
Torasemide Improves the Propionic Acid-Induced Autism in Rats: A Histopathological and Imaging Study
Objective: Autism spectrum disorder is a neurodevelopmental disease in which impaired social behaviors, impaired sociality, and restricted and repetitive behaviors are seen.
M. Doğan, Y. Albayrak, O. Erbaş
semanticscholar +1 more source
Background Torasemide is a potent loop diuretic with potential to treat congestive heart failure (CHF) in dogs. Objective Evaluate the efficacy and safety of torasemide compared to furosemide in dogs with first occurrence of CHF caused by degenerative ...
Beatrice Besche +4 more
doaj +1 more source
Advantages of the new loop diuretic torasemide over furosemide in patients with cirrhosis and ascites [PDF]
Torasemide is a new loop diuretic with a longer half-life and longer action than furosemide in healthy subjects. In order to evaluate the pharmacodynamic effects, single oral doses of furosemide (80 mg) and torasemide (20 mg), which were equipotent in ...
Bertheau-Reitha, Ute +4 more
core +1 more source
Improving Postdischarge Outcomes in Acute Heart Failure [PDF]
The global burden that acute heart failure (AHF) carries has remained unchanged over the past several decades (1). European registries (2–5) showed that 1-year outcome rates remain unacceptably high (Table 1) and confirm that hospitalization for AHF ...
Ambrosy, Andrew P. +8 more
core +1 more source

