Results 211 to 220 of about 320,551 (292)

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

Advanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch, Peter Goettig, Michael A. Nash, Juri Rappsilber, Nediljko Budisa   +4 more
wiley   +1 more source

Cost-utility analysis of lenvatinib and sorafenib for the first-line treatment of unresectable hepatocellular carcinoma in Vietnam: Evidence from a lower-middle income country. [PDF]

PLoS One
Do TX, Nguyen HT, Nguyen PTL, Kieu MTT, Duong TV, Pham VNH.   +5 more
europepmc   +1 more source

Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics

Advanced Science, EarlyView.
The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet, Priyanka Kumari, Sathyanarayana Paladugu, Damian Pociecha, Jakub Karcz, Przemysław Kula, Nataša Vaupotič, Ewa Górecka, Oleg D Lavrentovich   +8 more
wiley   +1 more source

Cost-utility and budget impact analyses of anaplastic lymphoma kinase inhibitors in Thailand. [PDF]

Sci Rep
Luksameesate P, Phatchararuangkit N, Soopairin S, Vinayanuwattikun C, Kulthanachairojana N, Taychakhoonavudh S.   +5 more
europepmc   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Deep learning framework based on ITOC optimization for coal spontaneous combustion temperature prediction: a coupled CNN-BiGRU-CBAM model. [PDF]

Sci Rep
Shao X, Liu W, Bai G, Chen Y, Liu Y, Guang J.   +5 more
europepmc   +1 more source

Knitted Pneumatic Fabrics for Dynamic Pressure Modulation in Personalized Healthcare Wearables

Advanced Science, EarlyView.
A pneumatic pressure‐regulating knitted fabric (PPKF) is developed, in which knitted pneumatic circuit enables the seamless integration of ultralow radial expansion pneumatic fiber into dual‐channel textile structure. By strategically modulating channel spacing, delivering adjustable dynamic pressures and clinically relevant gradient compression ratios.
Xiaoyu Chen, Jintu Fan, Rong Zheng, Qing Chen, Fengxin Sun, Huanhuan Liu   +5 more
wiley   +1 more source

Cost-effectiveness analysis of a biopsy-free diagnostic strategy for prostate cancer using mpMRI and PSMA-PET/CT. [PDF]

BJUI Compass
Tung JYM, Lau RS, Teo EPS, Chow KM, Ong JHW, Lu TS, Chen W, Li J, Yang X, Lee AY, Tan YG, Tay KJ, Thang SP, Lam WWC, Law YM, Ho HSS, Cheng CWS, Yuen JS, Chen K.   +18 more
europepmc   +1 more source

Direct Photocurrent Detection of Optical Vortex Based on the Orbital Photo Galvanic Effect: Progress, Challenge, and Perspective

Advanced Science, EarlyView.
Direct orbital angular momentum (OAM) detection through the orbital photogalvanic effect offers a scalable route for integrated optoelectronics. This perspective evaluates symmetry‐driven material selection and demonstrates how electrode matrices enable the resolution of complex, mixed OAM modes.
Jinluo Cheng, Dehong Yang, Weiming Wang, Chang Xu, Zipu Fan, Dong Sun   +5 more
wiley   +1 more source

The economic burden of brucellosis in Western Iran. [PDF]

Trop Med Health
Behzadifar M, Darvishi Teli B, Azari S, Bakhtiari A, Martini M, Behzadifar M.   +5 more
europepmc   +1 more source