Results 11 to 20 of about 5,956 (194)
Estrous cycle modulates fasting-induced torpor propensity via hypothalamic estrogen signalling [PDF]
Scientific ReportsTorpor is a state of transient hypometabolism and hypothermia that is engaged by many species in adverse conditions such as food scarcity. Chemo- or optoactivation of neurons in the hypothalamic preoptic area (POA) drives torpor-like hypometabolism and ...
Christopher J. Marshall +2 more
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Brainstem catecholaminergic neurons induce torpor during fasting by orchestrating cardiovascular and thermoregulation changes [PDF]
Nature CommunicationsTorpor, an adaptive hypometabolic state in response to fasting, is characterized by pronounced reductions in body temperature, heart rate, and thermogenesis.
Mingxiu Cheng +12 more
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Frontiers in Physiology, 2020 Daily torpor and hibernation (multiday torpor) are the most efficient means for energy conservation in endothermic birds and mammals and are used by many small species to deal with a number of challenges.
Fritz Geiser
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Neurons that regulate mouse torpor [PDF]
Nature, 2020 The advent of endothermy, which is achieved through the continuous homeostatic regulation of body temperature and metabolism1,2, is a defining feature of mammalian and avian evolution. However, when challenged by food deprivation or harsh environmental conditions, many mammalian species initiate adaptive energy-conserving survival strategies-including ...
Sinisa Hrvatin +11 more
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Platelet dynamics during natural and pharmacologically induced torpor and forced hypothermia.
PLoS ONE, 2014 Hibernation is an energy-conserving behavior in winter characterized by two phases: torpor and arousal. During torpor, markedly reduced metabolic activity results in inactivity and decreased body temperature.
Edwin L de Vrij +9 more
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Communications Biology, 2021 Ruslan Deviatiiarov et al. identify torpor-specific promoters with an enriched binding motif and the transcription factor ATF3 highly expressed during torpor deprivation.
Ruslan Deviatiiarov +7 more
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Induction of a Torpor-Like State by 5'-AMP Does Not Depend on H2S Production. [PDF]
PLoS ONE, 2015 Therapeutic hypothermia is used to reduce ischemia/reperfusion injury (IRI) during organ transplantation and major surgery, but does not fully prevent organ injury.
George J Dugbartey +4 more
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The Torpid State: Recent Advances in Metabolic Adaptations and Protective Mechanisms†
Frontiers in Physiology, 2021 Torpor and hibernation are powerful strategies enabling animals to survive periods of low resource availability. The state of torpor results from an active and drastic reduction of an individual’s metabolic rate (MR) associated with a relatively ...
Sylvain Giroud +9 more
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Scientific Reports, 2022 Torpor, and its differential expression, is essential to the survival of many mammals and birds. Physiological characteristics of torpor appear to vary between those species that express strict daily heterothermy and those capable of multiday hibernation,
Shannon E. Currie +2 more
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Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice
Nature Communications, 2020 Torpor is a state of reduced metabolism and body temperature that conserves energy when food is scarce. Here the authors show that estrogen-sensitive neurons in the hypothalamus regulate torpor in mice, maintaining torpor in both sexes but initiating ...
Zhi Zhang +17 more
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