Results 81 to 90 of about 5,956 (194)

Multiorgan ultrastructural changes in rats induced in synthetic torpor

Frontiers in Physiology
Torpor is a state used by several mammals to survive harsh winters and avoid predation, characterized by a drastic reduction in metabolic rate followed by a decrease in body temperature, heart rate, and many physiological variables.
Sara Salucci, Timna Hitrec, Emiliana Piscitiello, Alessandra Occhinegro, Luca Alberti, Ludovico Taddei, Sabrina Burattini, Marco Luppi, Domenico Tupone, Roberto Amici, Irene Faenza, Matteo Cerri   +11 more
doaj   +1 more source

Daily torpor and hibernation in birds and mammals

Biological Reviews, 2014
ABSTRACTMany birds and mammals drastically reduce their energy expenditure during times of cold exposure, food shortage, or drought, by temporarily abandoning euthermia, i.e. the maintenance of high body temperatures. Traditionally, two different types of heterothermy, i.e.
Thomas, Ruf, Fritz, Geiser
openaire   +2 more sources

Torpor induces reversible tau hyperphosphorylation and accumulation in mice expressing human tau

Acta Neuropathologica Communications
Tau protein hyperphosphorylation and aggregation are key pathological events in neurodegenerative tauopathies such as Alzheimer’s disease. Interestingly, seasonal hibernators show extensive tau hyperphosphorylation during torpor, i.e., the hypothermic ...
C. F. de Veij Mestdagh, M. E. Witte, W. Scheper, A. B. Smit, R. H. Henning, R. E. van Kesteren   +5 more
doaj   +1 more source

Hippocampal neuroimmune response in mice undergoing serial daily torpor induced by calorie restriction

Frontiers in Neuroanatomy
Hibernating animals demonstrate a remarkable ability to withstand extreme physiological brain changes without triggering adverse neuroinflammatory responses.
Valeria Cogut, Maaike Goris, Aukje Jansma, Marrit van der Staaij, Robert H. Henning   +4 more
doaj   +1 more source

Ghrelin is essential for lowering blood pressure during torpor

Frontiers in Endocrinology
IntroductionDaily torpor is an active hypothermic phenomenon that is observed in some mammals and birds during fasting. A decrease in blood pressure has also been observed in torpor; however, there remains a lack of knowledge of the underlying mechanism.
Kazuma Matsui, Takanori Ida, Kanae Oishi, Masayasu Kojima, Takahiro Sato   +4 more
doaj   +1 more source

Identification of hypothermia-inducing neurons in the preoptic area and activation of them by isoflurane anesthesia and central injection of adenosine

Journal of Physiological Sciences
Hibernation and torpor are not passive responses caused by external temperature drops and fasting but are active brain functions that lower body temperature.
Erika Uchino, Ikue Kusumoto-Yoshida, Hideki Kashiwadani, Yuichi Kanmura, Akira Matsunaga, Tomoyuki Kuwaki   +5 more
doaj   +1 more source

Sedative Agents, Synthetic Torpor, and Long-Haul Space Travel—A Systematic Review

Life
Background: With renewed interest in long-duration space missions, there is growing exploration into synthetic torpor as a countermeasure to mitigate physiological stressors.
Thomas Cahill, Nataliya Matveychuk, Elena Hardiman, Howard Rosner, Deacon Farrell, Gary Hardiman   +5 more
doaj   +1 more source

Remarks on Irritability and Torpor [PDF]

The Boston Medical and Surgical Journal
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openaire   +2 more sources

Testing for torpor [PDF]

Lab Animal, 2018
openaire   +1 more source

Clocks slide rather than freeze during torpor in the mouse. [PDF]

iScience
Hitrec T, Taddei L, Chrobok L, Elley M, Wheatley WSR, Pickering AE, Ambler MT.   +6 more
europepmc   +1 more source