Results 141 to 150 of about 5,815 (252)

Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure

open access: yesPhytotherapy Research, EarlyView.
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao   +6 more
wiley   +1 more source

Biomimetic robots driven by smart materials: Motion forms, stimulation methods and applications

open access: yesResponsive Materials, EarlyView.
Biomimetic robots enhance adaptability by mimicking biological systems, but rigid materials limit performance. Smart materials with stimuli responsiveness and shape adaptability enable more flexible actuation and improved environmental interaction.
Zeyu Yang   +8 more
wiley   +1 more source

Intelligent Continuum Micromachines in Complex Confined Spaces

open access: yesSmartBot, EarlyView.
The cover depicts a conceptual design for an intelligent continuum micromachine entering a target capsule used in fusion‐energy research through its slender gas‐fill tube. By combining route‐adaptive deformation, embedded sensing, and a functional end effector, the robot could inspect hidden defects, assess local conditions, and support localized ...
Huayang Sai   +7 more
wiley   +1 more source

Bioelectronic Wearable Sensors Produced by Computerized Embroidery Using a Dual Thread Approach

open access: yesSmall, EarlyView.
A dual‐thread embroidered SmartBra integrates silver‐plated and conductive‐polymer (PECOTEX) threads to enable simultaneous cardiac monitoring and open‐circuit potentiometric sensing of potassium and sodium in a breast milk substitute. The wearable platform is fabricated using computerized embroidery, offering a scalable, proof‐of‐concept route toward ...
Taliya Weinstein   +9 more
wiley   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

open access: yesSmart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song   +6 more
wiley   +1 more source

On-Limb Orbiting Robot: Proprioceptive Diameter Estimation and Orthogonal Grip-Orbit Control. [PDF]

open access: yesBiomimetics (Basel)
Tobar-Subía-Contento LM   +3 more
europepmc   +1 more source

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