Results 41 to 50 of about 8,385,794 (295)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Numerical Simulation on Effects of Phase Difference on Rock-Breaking Efficiency Under Compound Impact

Shiyou jixie, 2023
Previous researches on rock-breaking efficiency under compound impact neglect the effects of the phase difference between axial and torsional impact loads.Therefor,such effects were discussed.The single-cutter rock-breaking numerical model of PDC bit ...
Xi Yan, Wang Haoyu, Qi Yue, Tian Yudong, Li Jun, Wang Wei   +5 more
doaj  

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Experimental investigation of torsional vibration isolation using Magneto Rheological Elastomer

MATEC Web of Conferences, 2018
Rotating systems suffer from lateral and torsional vibrations which have detrimental effect on the roto-dynamic performance. Many available technologies such as vibration isolators and vibration absorbers deal with the torsional vibrations to a certain ...
Praveen Shenoy K, Singh Abhishek Kumar, Sai Aditya Raman K, Gangadharan K. V.   +3 more
doaj   +2 more sources

Impact torsional behavior and strengthening of reinforced concrete spandrel beams

Case Studies in Construction Materials, 2023
The exterior L-shaped spandrel beams frequently experience various forms of eccentric loading that induce torsional stress when used in parking structures.
Noor Ayaad, Nazar Oukaili
doaj   +1 more source

The Impact of Endurance Exercise Training on Left Ventricular Torsion

JACC: Cardiovascular Imaging, 2010
We sought to examine the effect of endurance exercise training (EET) on peak systolic left ventricular torsion (LVT) and peak early diastolic untwisting rate (UTR).Left ventricular (LV) structural adaptations to EET have been well characterized. LVT, a recognized marker of LV function in numerous cardiac diseases, has recently been investigated in the ...
Weiner, Rory B., Hutter, Adolph M., Wang, Francis, Kim, Jonathan, Weyman, Arthur E., Wood, Malissa J., Picard, Michael H., Baggish, Aaron L.   +7 more
openaire   +2 more sources

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Influence of boundary conditions and geometric imperfections on lateral–torsional buckling resistance of a pultruded FRP I-beam by FEA [PDF]

, 2013
Presented are results from geometric non-linear finite element analyses to examine the lateral torsional buckling (LTB) resistance of a Pultruded fibre reinforced polymer (FRP) I-beam when initial geometric imperfections associated with the LTB mode ...
Nguyen, T. T., Chan, Tak-Ming, Mottram, J. Toby   +2 more
core   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Study on ROP Enhancement of Composite Percussive Drilling in Deep Tight Shale

Xinjiang shiyou tianranqi
To address the challenges of high compressive strength，low drillability，and extended drilling time in the deep tight shale of the Mabei Fengcheng Formation，an experimental study on drilling parameter optimization for axial-torsional coupled percussive ...
MU Zongjie, QIU Zilun, FANG Yan, YANG Zhehua, SHI Jiangang, ZHANG Panpan   +5 more
doaj   +1 more source