Results 41 to 50 of about 63,940 (291)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

On the torsional energy of torus knots under infinitesimal bending

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2023
The article deals with the infinitesimal bending theory application to the knots theory. The impact of infinitesimal bending on the torsional energy at torus knots is considered, and the results show that it is not stationary under infinitesimal bending.
Maksimović Miroslav D., Rančić Svetozar R., Najdanović Marija S., Velimirović Ljubica S., Ljajko Eugen S.   +4 more
doaj   +1 more source

Influence of Variable Side-Stay Geometry on the Shimmy Dynamics of an Aircraft Dual-Wheel Main Landing Gear [PDF]

, 2013
Commercial aircraft are designed to fly but also need to operate safely and efficiently as vehicles on the ground. During taxiing, take-off, and landing the landing gear must operate reliably over a wide range of forward velocities and vertical loads ...
Howcroft, Chris, Krauskopf, Bernd, Lowenberg, Mark H, Neild, Simon A   +3 more
core   +2 more sources

A New Large Impact Torsion Testing Machine

Journal of the Society of Materials Science, Japan, 1966
The large impact torsion testing machine which has recently been designed and constructed by the present authors, has the capacity of 100kg-m and the rotating speed from 100rpm to 2600rpm. This machine is fit to make intermittent loading, the detection of axial stress caused during the torsional deformation and the tests under combined stress by adding
Seita SAKUI, Tadahisa NAKAMURA, Toshimitsu TSUMURA   +2 more
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Development of a switchable system for longitudinal and longitudinal-torsional vibration extraction [PDF]

, 2012
High-frequency/low-frequency drilling is an attractive technology for planetary exploration tools, and one which has seen considerable innovation in the techniques used to ensure rotation of the front-end cutting bit.
Harkness, Patrick, Lucas, Margaret
core  

Charge transport through a flexible molecular junction

, 2004
Vibrationally inelastic electron transport through a flexible molecular junction is investigated. The study is based on a mechanistic model for a biphenyl molecule between two metal electrodes.
Cizek, Martin, Domcke, Wolfgang, Thoss, Michael   +2 more
core   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Analysis of the effects of torsional impact tools on drill string stick–slip vibration

Energy Exploration & Exploitation
Torsional impactor is widely used in deep and ultra-deep wells because it can suppress stick–slip vibration and increase ROP. As the direct factor affecting torsional impactor effect, it's working parameters study is still not sufficient.
Chaoyi She, Jianhua Guo, Jie Wu, Qingsong Qiao, Beiqiao Meng, Yuting Zhang   +5 more
doaj   +1 more source

The effect of high-frequency torsional impacts on the dynamic response of a drill string in a stick state

Advances in Mechanical Engineering, 2019
Stick–slip vibration is common in the oil well drilling process and is detrimental to down-hole equipment and drilling efficiency. In recent years, a new type of drilling technology, torsional impact drilling, has been developed to mitigate the stick ...
Liping Tang, Wei He, Xiaohua Zhu
doaj   +1 more source