A double‐headed bis‐guanine (G) nucleotide (GG) was evaluated as a noncanonical building block in G‐quadruplexes (G4s). Biophysical and computational analyses reveal that GG can directly participate in G‐tetrads and strongly stabilize G4s in a position‐ and topology‐dependent manner. These findings establish design rules for using GG to engineer highly
Krista Urup +5 more
wiley +1 more source
Posterior Canal and Atypical Benign Paroxysmal Positional Vertigo: Development of a Predictive Model for Clinical Decision-Making. [PDF]
Jakobsen KM +7 more
europepmc +1 more source
On the Torsional Impact Loading of an Elastic Thick Plate
openaire +2 more sources
Several new chiral cyclic hypervalent iodine(III) reagents have been synthesized and characterized. Carbon‐based ligands were successfully installed onto the hypervalent iodine centers, giving thus access to novel chiral cyano‐, trifluoromethyl‐ or alkynyl‐bearing λ3‐iodanes.
Emmanuel Valzer +4 more
wiley +1 more source
Association Between Cross-Sectional Geometry and Cyclic Fatigue Resistance of Nickel-Titanium Endodontic Instruments: A Systematic Review. [PDF]
Kubatska M +8 more
europepmc +1 more source
Raman Optical Activity as a Tool to Monitor Polynucleotide Conformation in Solutions
Raman optical activity (ROA) studies of nucleic acids have been hindered by limited computational tools to link the spectra to the structure. The study shows that accurate density functional simulations are possible for model nucleotides, bringing more information about molecular geometry and dynamics in solutions.
Mohammed Siddhique Para Kkadan +5 more
wiley +1 more source
Interlocking plate compared with conventional pin fixation for undisplaced femoral neck fractures: a randomized controlled trial with radiostereometric analysis. [PDF]
Høgevold M +3 more
europepmc +1 more source
Reactions of 10‐mesityl‐1,8‐diphenylanthracene with DDQ/TfOH produced three products via sequential formation of a five‐ or seven‐membered ring. Unexpectedly, the triply cyclized product with a rubicene substructure was formed through cyclization involving 1,2‐methyl shift.
Tatsuhiro Sasaki +2 more
wiley +1 more source
Integrated multifactor assessment of road geometry, vehicle types and weather diversity on bilateral transverse slopes: Bridging gaps in dynamic modeling. [PDF]
Moharami M +3 more
europepmc +1 more source
Five heteroleptic iridium(III) complexes bearing cyclometalated 2,4‐diphenylpyridinato ligands were synthesized and their electrochemiluminescence (ECL) investigated. Two different coreactants were evaluated: tri‐n‐propylamine and benzoyl peroxide under anodic and cathodic potentials, respectively.
Ovini Jayawardana +6 more
wiley +1 more source

